This database contains 182 studies, archived under the term: "physiology"
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What effect does a structured home-based exercise programme have on people with Huntington’s disease? A randomized, controlled pilot study
Khalil, H.,
Quinn, L.,
van Deursen, R.,
Dawes, H.,
Playle, R.,
Rosser, A.,
Busse, M.
Objective: The aim of this study was to explore feasibility, safety and outcome of an exercise intervention in people with Huntington’s disease.; Design: A randomized controlled pilot trial.; Setting: A home-based exercise programme.; Subjects: A total of 25 subjects with early to mid-stage Huntington’s disease.; Intervention: Subjects were randomly allocated to either an exercise intervention […]
Long-term statin therapy is associated with better episodic memory in aged familial hypercholesterolemia patients in comparison with population controls
Hyttinen, Laura,
TuulioHenriksson, Annamari,
Vuorio, Alpo F.,
Kuosmanen, Noora,
Härkänen, Tommi,
Koskinen, Seppo,
Strandberg, Timo E.
The cognitive status of aged familial hypercholesterolemia (FH) patients treated with long-term statin therapy was compared with that of population controls. A comprehensive cohort of 43 elderly (age > or = 65 years) patients all with the same FH North Karelia mutation living in North Karelia (eastern Finland) was identified, 37 of whom (aged 65 […]
Influence of regular exercise on subjective sense of burden and physical symptoms in community-dwelling caregivers of dementia patients: a randomized controlled trial
Hirano, Akemi,
Suzuki, Yusuke,
Kuzuya, Masafumi,
Onishi, Joji,
Ban, Nobutaro,
Umegaki, Hiroyuki
With an aim to improve quality of life in caregivers of dementia patients, we examined the effect of regular exercise on caregivers’ sense of burden and their physical symptoms. Participants were 31 elderly caregivers living with older patients diagnosed with Alzheimer’s-type dementia. They were randomly assigned to either the intervention group, who were prescribed regular […]
Antihypertensive therapy and cerebral hemodynamics in executive mild cognitive impairment: results of a pilot randomized clinical trial
Hajjar, Ihab,
Hart, Meaghan,
Chen, Yu-Ling,
Mack, Wendy,
Novak, Vera,
C. Chui, Helena,
Lipsitz, Lewis
Objectives: To compare the effects of three antihypertensive medications on cerebral hemodynamic and cognitive function in hypertensive individuals with executive dysfunction.; Design: Double-blind randomized clinical trial.; Setting: Community.; Participants: Fifty-three individuals aged 60 and older with hypertension and executive dysfunction.; Intervention: Lisinopril, candesartan, or hydrochlorothiazide for 1 year.; Measurements: Cerebral blood flow velocity (BFV; transcranial […]
Evaluating proFamilies-dementia: adopting photovoice to capture clinical significance
Dementia is a challenging chronic illness that affects the patients and their families. Families often perform a full-time, specialised role, which requires expert knowledge and skills. This paper describes the evaluation of proFamilies-dementia (a programme developed to support families that care for a relative with dementia) using an innovative participatory methodology: photovoice, a qualitative method […]