This database contains 114 studies, archived under the term: "mild cognitive impairment"
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In vivo assessment of amyloid-β deposition in nondemented very elderly subjects
Mathis, Chester A.,
Kuller, Lewis H.,
Klunk, William E.,
Snitz, Beth E.,
Price, Julie C.,
Weissfeld, Lisa A.,
Rosario, Bedda L.,
Lopresti, Brian J.,
Saxton, Judith A.,
Aizenstein, Howard J.,
McDade, Eric M.,
Kamboh, M. Ilyas,
DeKosky, Steven T.,
Lopez, Oscar L.
Objective: This study examined amyloid-β (Aβ) deposition in 190 nondemented subjects aged ≥82 years to determine the proportion of Aβ-positive scans and associations with cognition, apolipoprotein E (APOE) status, brain volume, and Ginkgo biloba (Gb) treatment.; Methods: Subjects who agreed to participate had a brain magnetic resonance imaging and positron emission tomography scan with (11) […]
Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial
Martínez-Lapiscina, Elena H,
Clavero, P.,
Toledo, E.,
San Julian, B.,
Sanchez-Tainta, A.,
Corella, D.,
Lamuela-Raventos, R. M.,
Martinez, J. A.,
Martinez-Gonzalez, M. Á.
Objective: To assess the effect on cognition of a controlled intervention testing Mediterranean diets (MedDiet).; Design: Randomized trial after 6.5 years of nutritional intervention.; Setting: Eight primary care centers affiliated to the University of Navarra.; Participants: A random subsample of 285 participants (95 randomly allocated to each of 3 groups) of the PREDIMED-NAVARRA trial. All […]
Informant-reported cognitive symptoms that predict amnestic mild cognitive impairment
Background: Differentiating amnestic mild cognitive impairment (aMCI) from normal cognition is difficult in clinical settings. Self-reported and informant-reported memory complaints occur often in both clinical groups, which then necessitates the use of a comprehensive neuropsychological examination to make a differential diagnosis. However, the ability to identify cognitive symptoms that are predictive of aMCI through informant-based […]
Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool
Liu, Yawu,
Mattila, Jussi,
Ruiz, Miguel Ángel Muñoz,
Paajanen, Teemu,
Koikkalainen, Juha,
van Gils, Mark,
Herukka, Sanna-Kaisa,
Waldemar, Gunhild,
Lötjönen, Jyrki,
Soininen, Hilkka
Purpose: To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA) on MRI and CSF biomarkers.; Methods: Altogether 391 MCI cases (158 […]
Mediterranean diet and cognitive function: a French study
Kesse-Guyot, E.,
Andreeva, V. A.,
Lassale, C.,
Ferry, M.,
Jeandel, C.,
Hercberg, S.,
Galan, P.
Background: Evidence on the association between Mediterranean diet (MedDiet) adherence and cognition is presently inconsistent.; Objectives: The aims of this study were to investigate the association between midlife MedDiet adherence and cognitive performance assessed 13 y later among participants in the SU.VI.MAX (Supplementation with Vitamins and Mineral Antioxidants) study and to test the hypothesis of […]
Long-term effects of group therapy for patients with mild cognitive impairment and their significant others: a 6- to 8-month follow-up study
Banningh, L. W. A. J.-W.,
Roelofs, S. C. F.,
Vernooij-Dassen, M. J. F. J.,
Prins, J. B.,
Rikkert, M. G. M. O.,
Kessels, R. P. C.
The present study examines the long-term effects of a 10-session cognitive behavioural group therapy for patients with mild cognitive impairment (MCI) and their significant others 6 to 8 months after completion of the intervention. Forty-seven MCI patients and 47 significant others participated in the follow-up assessment. Results of the RAND-36, Illness Cognition Questionnaire, IQCODE, GDS-15 […]