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This database contains 542 studies, archived under the term: "middle aged"

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A home programme for patients with cognitive dysfunction: a pilot study

Objective: To evaluate the effectiveness of a 12-week individualized home programme of rehabilitation for patients with cognitive impairment.; Methods: Six patients with cognitive dysfunction, after haemorrhagic stroke, participated in this study. A programme was carried out in the home environment that consisted of four mixed training programmes: cognitive remediation therapy, story retelling, cognitive enhancing games […]

A validity study of the Working Group’s Autobiographical Memory Test for individuals with moderate to severe intellectual disability

The purpose of the present study was to investigate the validity of the Working Group’s Autobiographical Memory Test as a dementia screening tool for individuals with moderate to severe intellectual disabilities (ID). Twenty-one participants with Dementia of Alzheimer’s Type (DAT) and moderate to severe ID and 42 controls with similar levels of ID were tested. […]

A pilot study of a test for visual recognition memory in adults with moderate to severe intellectual disability

Objective assessment of memory functioning is an important part of evaluation for Dementia of Alzheimer Type (DAT). The revised Picture Recognition Memory Test (r-PRMT) is a test for visual recognition memory to assess memory functioning of persons with intellectual disabilities (ID), specifically targeting moderate to severe ID. A pilot study was performed to investigate whether […]

Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial

Unlabelled: Patients with cognitive impairment (CI) often do not receive secondary fracture prevention. Use of zoledronic acid led to a similar reduction in re-fracture risk but the survival benefit was limited to those without CI.; Introduction: We tested whether the effects of id (Zol) on re-frazoledronic accture and mortality differed in patients presenting with a […]

Clock drawing in the Montreal Cognitive Assessment: recommendations for dementia assessment

Background: Clock drawing is part of the Montreal Cognitive Assessment (MoCA) test but may have administration and scoring limitations. We assessed (1) the reliability of the MoCA clock criteria relative to a published error scoring approach, (2) whether command-only administration could distinguish dementia from cognitively intact individuals and (3) the value of adding a clock […]

High fruit and vegetable intake is positively correlated with antioxidant status and cognitive performance in healthy subjects

A higher daily intake of fruits and vegetables in healthy elderly is associated with an improved antioxidant status in comparison to subjects consuming diets poor in fruits and vegetables, but the impact on cognitive performance is unclear. Healthy community dwellers (45 to 102 years old, n=193) underwent cognitive testing and blood withdrawal for the measurement […]

Contribution of relaxation to a psychoeducational intervention program for family carers of persons with Alzheimer’s disease

Unlabelled: Family caregivers of people with Alzheimer’s disease are at high risk of psychological and physical morbidity due to the daily caring experience.; Objectives: to evaluate the impact of a psychoeducational program involving relaxation techniques on caregivers’ burden and mental health status.; Methods: in this prospective study, 50 family caregivers were randomly assigned to one […]

Underestimation of cognitive impairment by Mini-Mental State Examination versus the Montreal Cognitive Assessment in patients with transient ischemic attack and stroke: a population-based study

Background and Purpose: The Mini-Mental State Examination (MMSE) is insensitive to mild cognitive impairment and executive function. The more recently developed Montreal Cognitive Assessment (MoCA), an alternative, brief 30-point global cognitive screen, might pick up more cognitive abnormalities in patients with cerebrovascular disease.; Methods: In a population-based study (Oxford Vascular Study) of transient ischemic attack […]

Prediction of manifest Huntington’s disease with clinical and imaging measures: a prospective observational study

Background: Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington’s disease is well known, improved prediction of onset would be advantageous for clinical trial design and prognostic counselling. We compared various measures for tracking progression and predicting conversion to manifest Huntington’s disease.; Methods: In this prospective observational study, we assessed […]

Validation of the Hungarian version of Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) in patients with mild cognitive impairment

Introduction: Early recognition of mild cognitive impairment (MCI) has increasing clinical relevance in the treatment process of dementia, since it is considered as prodromal period. A great variety of instruments have been developed for measuring cognitive performance of the demented patients. The cognitive subscale of the Alzheimer’s Disease Assessment Scale (ADAS-Cog) is one of the […]

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