This database contains 542 studies, archived under the term: "middle aged"
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A home programme for patients with cognitive dysfunction: a pilot study
Pyun, Sung-Bom,
Yang, Heeseung,
Lee, Sangil,
Yook, Jinsook,
Kwon, Jaesung,
Byun, Eun-Mi
Objective: To evaluate the effectiveness of a 12-week individualized home programme of rehabilitation for patients with cognitive impairment.; Methods: Six patients with cognitive dysfunction, after haemorrhagic stroke, participated in this study. A programme was carried out in the home environment that consisted of four mixed training programmes: cognitive remediation therapy, story retelling, cognitive enhancing games […]
Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial
Prieto-Alhambra, D.,
Judge, A.,
Arden, N. K.,
Cooper, C.,
Lyles, K. W.,
Javaid, M. K.
Unlabelled: Patients with cognitive impairment (CI) often do not receive secondary fracture prevention. Use of zoledronic acid led to a similar reduction in re-fracture risk but the survival benefit was limited to those without CI.; Introduction: We tested whether the effects of id (Zol) on re-frazoledronic accture and mortality differed in patients presenting with a […]
Clock drawing in the Montreal Cognitive Assessment: recommendations for dementia assessment
Price, Catherine C.,
Cunningham, Holly,
Coronado, Nicole,
Freedland, Alana,
Cosentino, Stephanie,
Penney, Dana L.,
Penisi, Alfio,
Bowers, Dawn,
Okun, Michael S.,
Libon, David J.
Background: Clock drawing is part of the Montreal Cognitive Assessment (MoCA) test but may have administration and scoring limitations. We assessed (1) the reliability of the MoCA clock criteria relative to a published error scoring approach, (2) whether command-only administration could distinguish dementia from cognitively intact individuals and (3) the value of adding a clock […]
High fruit and vegetable intake is positively correlated with antioxidant status and cognitive performance in healthy subjects
Polidori, M. Cristina,
Praticó, Domenico,
Mangialasche, Francesca,
Mariani, Elena,
Aust, Olivier,
Anlasik, Timur,
Mang, Ni,
Pientka, Ludger,
Stahl, Wilhelm,
Sies, Helmut,
Mecocci, Patrizia,
Nelles, Gereon
A higher daily intake of fruits and vegetables in healthy elderly is associated with an improved antioxidant status in comparison to subjects consuming diets poor in fruits and vegetables, but the impact on cognitive performance is unclear. Healthy community dwellers (45 to 102 years old, n=193) underwent cognitive testing and blood withdrawal for the measurement […]
Prediction of manifest Huntington’s disease with clinical and imaging measures: a prospective observational study
Paulsen, Jane S.,
Long, Jeffrey D,
Ross, Christopher A,
Harrington, Deborah L,
Erwin, Cheryl J,
Williams, Janet K,
Westervelt, Holly James,
Johnson, Hans J,
Aylward, Elizabeth H,
Zhang, Ying,
Bockholt, H Jeremy,
Barker, Roger A
Background: Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington’s disease is well known, improved prediction of onset would be advantageous for clinical trial design and prognostic counselling. We compared various measures for tracking progression and predicting conversion to manifest Huntington’s disease.; Methods: In this prospective observational study, we assessed […]