This database contains 366 studies, archived under the term: "methods"
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Cognitive testing in non-demented Turkish immigrants–comparison of the RUDAS and the MMSE
Methods for culturally and linguistically appropriate cognitive testing of elderly minority populations are lacking in Europe. The aim of this study was to compare performance on the Rowland Universal Dementia Assessment Scale (RUDAS) and the Mini Mental State Examination (MMSE) in Turkish immigrants in Denmark and determine the impact of demographic and health-related variables on […]
Efficacy of musical interventions in dementia: evidence from a randomized controlled trial
Narme, Pauline,
Clément, Sylvain,
Ehrlé, Nathalie,
Schiaratura, Loris,
Vachez, Sylvie,
Courtaigne, Bruno,
Munsch, Frédéric,
Samson, Séverine
Although musical interventions have recently gained popularity as a non-pharmacological treatment in dementia, there is still insufficient evidence of their effectiveness. To investigate this issue, a single-center randomized controlled trial was conducted with forty-eight patients with Alzheimer’s disease or mixed dementia to compare the effects of music versus cooking interventions in the emotional, cognitive, and […]
Animal-assisted activity and emotional status of patients with Alzheimer’s disease in day care
Mossello, Enrico,
Ridolfi, Alessandro,
Mello, Anna Maria,
Lorenzini, Giulia,
Mugnai, Francesca,
Piccini, Carolina,
Barone, Domenico,
Peruzzi, Anna,
Masotti, Giulio,
Marchionni, Niccolò
Background: Preliminary studies suggest beneficial effects of animal-assisted activities (AAA) on behavioral and psychological symptoms of dementia (BPSD), but data are inconsistent. This study aimed to assess the effect of AAA with dogs on cognition, BPSD, emotional status and motor activity in severe Alzheimer’s disease (AD).; Methods: Ten patients attending an Alzheimer Day Care Center […]
A randomized clinical trial of Behavioral Activation (BA) therapy for improving psychological and physical health in dementia caregivers: results of the Pleasant Events Program (PEP)
Moore, Raeanne C.,
Chattillion, Elizabeth A.,
Ceglowski, Jennifer,
Ho, Jennifer,
von Känel, Roland,
Mills, Paul J.,
Ziegler, Michael G.,
Patterson, Thomas L.,
Grant, Igor,
Mausbach, Brent T.
Dementia caregiving is associated with elevations in depressive symptoms and increased risk for cardiovascular diseases (CVD). This study evaluated the efficacy of the Pleasant Events Program (PEP), a 6-week Behavioral Activation intervention designed to reduce CVD risk and depressive symptoms in caregivers. One hundred dementia family caregivers were randomized to either the 6-week PEP intervention […]
Memantine versus donepezil in mild to moderate Alzheimer’s disease: a randomized trial with magnetic resonance spectroscopy
Modrego, P. J.,
Fayed, N.,
Errea, J. M.,
Rios, C.,
Pina, M. A.,
Sarasa, M.
Background and Purpose: To compare memantine with the most prescribed cholinesterase inhibitor (donepezil) from a clinical viewpoint when administered in early phases of Alzheimer disease (AD), and to find out whether memantine may produce changes in brain metabolite concentrations in comparison with donepezil.; Methods: In this comparative rater-blinded parallel group randomized trial we recruited a […]
Evaluation of Parkinson disease and Alzheimer disease with the use of neuromelanin MR imaging and (123)I-metaiodobenzylguanidine scintigraphy
Miyoshi, F.,
Ogawa, T.,
Kitao, S.- i.,
Kitayama, M.,
Shinohara, Y.,
Takasugi, M.,
Fujii, S.,
Kaminou, T.
Background and Purpose: Progressive changes in the substantia nigra pars compacta and locus ceruleus of patients with Parkinson disease and Alzheimer disease visualized by neuromelanin MRI and cardiac postganglionic sympathetic nerve function on (123)I-metaiodobenzylguanidine scintigraphy have not been fully evaluated. We compared the diagnostic value of these modalities among patients with early Parkinson disease, late […]
Evaluating cognition in an elderly cohort via telephone assessment
Mitsis, Effie M.,
Jacobs, Diane,
Luo, Xiaodong,
Andrews, Howard,
Andrews, Karen,
Sano, Mary
Objective: Longitudinal neuropsychological assessment provides the opportunity to observe the earliest transition to cognitive impairment in healthy, elderly individuals. We examined the feasibility, and its comparability to in-person assessment, of a telephone administered battery of established neuropsychological measures of cognitive functioning in healthy, elderly women.; Methods: Fifty-four women (age = 79 +/- 7.7; education = […]
Effect of a computerized brain exercise program on cognitive performance in older adults
Miller, Karen J.,
Dye, Richelin V.,
Kim, Jeanne,
Jennings, Julia L.,
O'Toole, Elizabeth,
Wong, Julie,
Siddarth, Prabha
Objectives: Research indicates an association between stimulating mental activities and better memory performance as people age, but studies on computerized mental stimulation programs are limited. We explored whether computerized brain training exercises improved cognitive performance in older adults.; Methods: In local retirement communities, a convenience sample was randomized into an intervention group (N = 36), […]