Stallard, Eric, Kinosian, Bruce, Zbrozek, Arthur S., Yashin, Anatoliy I., Glick, Henry A., Stern, Yaakov

Objectives: To estimate and validate a multiattribute model of the clinical course of Alzheimer disease (AD) from mild AD to death in a high-quality prospective cohort study, and to estimate the impact of hypothetical modifications to AD progression rates on costs associated with Medicare and Medicaid services. Data and Methods: The authors estimated sex-specific longitudinal […]

Dobbs, Debra, Meng, Hongdao, Hyer, Kathyrn, Volicer, Ladi

Objective: This study examined the impact of hospice enrollment on the probabilities of hospital and nursing home admissions among a sample of frail dual-eligible assisted living (AL) residents.; Design: The study used a retrospective cohort design. We estimated bivariate probit models with 2 binary outcome variables: any hospital admissions and any nursing home admissions after […]

Fosbøl, Emil L., Peterson, Eric D., Holm, Ellen, Gislason, Gunnar H., Zhang, Yinghong, Curtis, Lesley H., Køber, Lars, Iwata, Isao, Torp-Pedersen, Christian, Setoguchi, Soko

Objectives: To compare the cardiovascular safety of currently marketed dementia medications in new users in the United States and Denmark.; Design: Retrospective cohort study.; Setting: Nationally representative sample of Medicare beneficiaries from 2006 through 2009 and nationwide Danish administrative registries from 1997 through 2007.; Participants: Individuals treated with a dementia medication aged 65 and older.; […]

Hebert, Paul L., McBean, Alexander Marshall, O'Connor, Heidi, Frank, Barbara, Good, Charles, Maciejewski, Matthew L.

Background: Centrally active (CA) angiotensin-converting enzyme inhibitors (ACEIs) are able to cross the blood–brain barrier. Small observational studies and mouse models suggest that use of CA versus non-CA ACEIs is associated with a reduced incidence of Alzheimer’s disease and related dementias (ADRD).; Objective: The aim of this research was to assess the effect of CA […]

Duru, O. Kenrik, Ettner, Susan L., Vassar, Stefanie D., Chodosh, Joshua, Vickrey, Barbara G.

Objective: To calculate intervention costs and the potential cost offset of a care management intervention that substantially improved the quality of dementia care.; Study Design: From both a payer perspective and a social planner perspective, we analyzed data from a cluster randomized controlled trial (RCT) evaluating this intervention versus usual care. The RCT included 408 […]

Brown, Arleen F., Vassar, Stefanie D., Connor, Karen I., Vickrey, Barbara G.

Objectives: To examine educational gradients in dementia care and whether the effect of a dementia collaborative care management intervention varied according to the educational attainment of the informal caregiver.; Design: Analysis of data from a cluster-randomized controlled trial.; Setting: Eighteen clinics in three healthcare organizations in southern California.; Participants: Dyads of Medicare recipients aged 65 […]