This database contains 4 studies, archived under the term: "indiana"
Alzheimer’s disease multiple intervention trial (ADMIT): study protocol for a randomized controlled clinical trial
Callahan, Christopher M.,
Boustani, Malaz A.,
Schmid, Arlene A.,
Austrom, Mary G.,
Miller, Douglas K.,
Gao, Sujuan,
Morris, Carrie S.,
Vogel, Mickey,
Hendrie, Hugh C.
Background: Given the current lack of disease-modifying therapies, it is important to explore new models of longitudinal care for older adults with dementia that focus on improving quality of life and delaying functional decline. In a previous clinical trial, we demonstrated that collaborative care for Alzheimer’s disease reduces patients’ neuropsychiatric symptoms as well as caregiver […]
Medication adherence and tolerability of Alzheimer’s disease medications: study protocol for a randomized controlled trial
Campbell, Noll L.,
Dexter, Paul,
Perkins, Anthony J.,
Gao, Sujuan,
Li, Lang,
Skaar, Todd C.,
Frame, Amie,
Hendrie, Hugh C.,
Callahan, Chris M.,
Boustani, Malaz A.
Background: The class of acetylcholinesterase inhibitors (ChEI), including donepezil, rivastigmine, and galantamine, have similar efficacy profiles in patients with mild to moderate Alzheimer’s disease (AD). However, few studies have evaluated adherence to these agents. We sought to prospectively capture the rates and reasons for nonadherence to ChEI and determine factors influencing tolerability and adherence.; Methods/design: […]
Effects of age, gender, education and race on two tests of language ability in community-based older adults
Snitz, Beth E.,
Unverzagt, Frederick W.,
Chang, Chung-Chou H.,
Bilt, Joni Vander,
Gao, Sujuan,
Saxton, Judith,
Hall, Kathleen S.,
Ganguli, Mary
Background: Neuropsychological tests, including tests of language ability, are frequently used to differentiate normal from pathological cognitive aging. However, language can be particularly difficult to assess in a standardized manner in cross-cultural studies and in patients from different educational and cultural backgrounds. This study examined the effects of age, gender, education and race on performance […]
Optimal blood pressure for cognitive function: findings from an elderly African-American cohort study
Liu, Hai,
Gao, Sujuan,
Hall, Kathleen S.,
Unverzagt, Frederick W.,
Lane, Kathleen A.,
Callahan, Christopher M.,
Hendrie, Hugh C.
Objectives: To report the results from a prospective cohort study on the association between blood pressure (BP) and cognitive function in elderly African Americans.; Design: Prospective cohort study conducted from 1997 to 2009.; Setting: Community-based study in Indianapolis.; Participants: African Americans aged 65 years or older (N = 3,145).; Measurements: At each assessment, participant cognitive […]