This database contains 1231 studies, archived under the term: "humans"
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Cognitive testing in non-demented Turkish immigrants–comparison of the RUDAS and the MMSE
Methods for culturally and linguistically appropriate cognitive testing of elderly minority populations are lacking in Europe. The aim of this study was to compare performance on the Rowland Universal Dementia Assessment Scale (RUDAS) and the Mini Mental State Examination (MMSE) in Turkish immigrants in Denmark and determine the impact of demographic and health-related variables on […]
Validation of the Rowland Universal Dementia Assessment Scale for multicultural screening in Danish memory clinics
Nielsen, T. Rune,
Andersen, Birgitte Bo,
Gottrup, Hanne,
Lützhøft, Jan H.,
Høgh, Peter,
Waldemar, Gunhild
Background/aims: The Rowland Universal Dementia Assessment Scale (RUDAS) is a brief cognitive screening test that was developed to detect dementia in multicultural populations. The RUDAS has not previously been validated in multicultural populations outside of Australia. The aim of this study was to evaluate the diagnostic accuracy of the RUDAS in a multicultural sample of […]
Montreal cognitive assessment performance in patients with Parkinson’s disease with “normal” global cognition according to mini-mental state examination score
Nazem, Sarra,
Siderowf, Andrew D.,
Duda, John E.,
Ten Have, Tom,
Colcher, Amy,
Horn, Stacy S.,
Moberg, Paul J.,
Wilkinson, Jayne R.,
Hurtig, Howard I.,
Stern, Matthew B.,
Weintraub, Daniel
Objectives: To examine Montreal Cognitive Assessment (MoCA) performance in patients with Parkinson’s disease (PD) with “normal” global cognition according to Mini-Mental State Examination (MMSE) score.; Design: A cross-sectional comparison of the MoCA and the MMSE.; Setting: Two movement disorders centers at the University of Pennsylvania and the Philadelphia Veterans Affairs Medical Center.; Participants: A convenience […]
The safety, tolerability, pharmacokinetics and cognitive effects of GSK239512, a selective histamine H₃ receptor antagonist in patients with mild to moderate Alzheimer’s disease: a preliminary investigation
Nathan, Pradeep J.,
Boardley, Rebecca,
Scott, Nicola,
Berges, Alienor,
Maruff, Paul,
Sivananthan, Tharani,
Upton, Neil,
Lowy, Martin T.,
Nestor, Peter J.,
Lai, Robert
Background: The histamine H3 receptor plays a critical role in the negative neuromodulation of neurotransmitters involved in cognitive function. H3 receptor antagonists/inverse agonists have been shown to exert pro-cognitive effects in pre-clinical models. GSK239512 is a potent and selective H₃ receptor antagonist developed for the treatment of cognitive dysfunction in neurodegenerative disorders. In this study […]
Efficacy of musical interventions in dementia: evidence from a randomized controlled trial
Narme, Pauline,
Clément, Sylvain,
Ehrlé, Nathalie,
Schiaratura, Loris,
Vachez, Sylvie,
Courtaigne, Bruno,
Munsch, Frédéric,
Samson, Séverine
Although musical interventions have recently gained popularity as a non-pharmacological treatment in dementia, there is still insufficient evidence of their effectiveness. To investigate this issue, a single-center randomized controlled trial was conducted with forty-eight patients with Alzheimer’s disease or mixed dementia to compare the effects of music versus cooking interventions in the emotional, cognitive, and […]
The effect of Baroque music on behavioural disturbances in patients with dementia
Nair, Balakrishnan Kichu,
Heim, Christian,
Krishnan, Chitra,
D'Este, Catherine,
Marley, John,
Attia, John
Aim: To study the effect of Baroque music in people with dementia.; Methods: Patients in a multicultural dementia-specific aged care facility were subjected to Baroque music in a cross-over study.; Results: There were significantly more behavioural disturbances during the weeks when Baroque music was played compared to control periods (0.2 more episodes per week, P […]
Exploring the effect of companion robots on emotional expression in older adults with dementia: a pilot randomized controlled trial
Moyle, Wendy,
Cooke, Marie,
Beattie, Elizabeth,
Jones, Cindy,
Klein, Barbara,
Cook, Glenda,
Gray, Chrystal
This pilot study aimed to compare the effect of companion robots (PARO) to participation in an interactive reading group on emotions in people living with moderate to severe dementia in a residential care setting. A randomized crossover design, with PARO and reading control groups, was used. Eighteen residents with mid- to late-stage dementia from one […]