Berr, Claudine, Portet, Florence, Carrière, Isabelle, Akbaraly, Tasnime N., Feart, Catherine, Gourlet, Véronique, Combe, Nicole, Barberger-Gateau, Pascale, Ritchie, Karen

Background: Olive oil is a major component of the Mediterranean diet suggested to be beneficial to counteract Alzheimer’s disease.; Aim Of the Study: Our objective was to examine the association between olive oil use, cognitive deficit and cognitive decline in a large elderly population.; Methods: We followed 6,947 subjects with a brief baseline food frequency […]

Babai, Samy, Auriche, Pascal, Le-Louët, Hervé

Background: Since donepezil and memantine are currently used for treating Alzheimer’s disease, it is interesting to analyse, reassess and compare their safety profile in order to promote a better use.; Methods: All spontaneous reports of suspected serious adverse drug reactions with donepezil alone and with memantine alone recorded in the French Pharmacovigilance Database during 6 […]

Annweiler, C., Rolland, Y., Schott, A.M., Blain, H., Vellas, B., Beauchet, O.

Background: Hypovitaminosis D has been cross-sectionally associated with dementia and stroke. The objective of this longitudinal study was to determine whether serum vitamin D deficiency at baseline could predict the onset of non-Alzheimer dementias (NAD) within 7 years among older women.; Methods: Forty high-functioning older women (78.4 years, 76.4/82.0; median, 25th/75th percentile) from the EPIDOS […]

Ancelin, Marie-Laure, Carrière, Isabelle, Barberger-Gateau, Pascale, Auriacombe, Sophie, Rouaud, Olivier, Fourlanos, Spiros, Berr, Claudine, Dupuy, Anne-Marie, Ritchie, Karen

The aim of this prospective cohort study was to evaluate the effects of lipid lowering agent (LLA) intake on cognitive function in 6,830 community-dwelling elderly persons. Cognitive performance (global cognitive functioning, visual memory, verbal fluency, psychomotor speed, and executive function), clinical diagnosis of dementia, and fibrate and statin use, were evaluated at baseline, and 2, […]