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This database contains 40 studies, archived under the term: "cost of illness"

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Exercise rehabilitation on home-dwelling patients with Alzheimer’s disease–a randomized, controlled trial. Study protocol

Background: Besides cognitive decline, Alzheimer’s disease (AD) leads to physical disability, need for help and permanent institutional care. The trials investigating effects of exercise rehabilitation on physical functioning of home-dwelling older dementia patients are still scarce. The aim of this study is to investigate the effectiveness of intensive exercise rehabilitation lasting for one year on […]

Use of the Tailored Activities Program to reduce neuropsychiatric behaviors in dementia: an Australian protocol for a randomized trial to evaluate its effectiveness

Background: Behavioral and psychological symptoms of dementia (BPSD) are often considered to be the greatest challenge in dementia care, leading to increased healthcare costs, caregiver burden, and placement into care facilities. With potential for pharmacological intervention to exacerbate behaviors or even lead to mortality, the development and rigorous testing of non-pharmacological interventions is vital. A […]

Practice example: neurodegenerative disorders: randomised controlled multicentre trial of home-based occupational therapy for patients with dementia

This paper summarises the methods and results of a seven-centre, single-blind, parallel group, actively controlled randomised trial evaluating the effectiveness of a Dutch 10-session community occupational therapy programme for patients with mild to moderate Alzheimer’s disease in German routine healthcare. Methodological aspects for future research on complex psychosocial interventions are discussed. (As supplied by publisher). […]

Do nurse-led skill training interventions affect informal caregivers’ out-of-pocket expenditures?

Purpose Of the Study: This paper is a report of a study of the Assistance, Support, and Self-health Initiated through Skill Training (ASSIST) randomized control trial. The aim of this paper is to understand whether participating in ASSIST significantly changed the out-of-pocket (OOP) costs for family caregivers of Alzheimer’s disease (AD) or Parkinson’s disease (PD) […]

Differential perceptions of quality of life (QoL) in community-dwelling persons with mild-to-moderate dementia

Background: Discordance between patient- and caregiver-reported quality of life (QoL) is well recognized. This study sought to (i) identify predictors of discrepancy between patient- and caregiver-rated QoL amongst community-dwelling persons with mild-to-moderate dementia, and (ii) differentiate between patients who systematically rate their QoL lower versus those who rate their QoL higher relative to their caregiver […]

Memantine for treatment of behavioural disturbances and psychotic symptoms in moderate to moderately severe Alzheimer dementia: a naturalistic study in outpatient services in Austria

We conducted an open, 16-week study on the efficacy of memantine on behavioral disturbances and psychotic symptoms in moderate to moderately severe Alzheimer s disease in daily routine. Fifty-three patients of 20 outpatient centers in Austria were recruited. The Neuropsychiatric Inventory (NPI) was defined as main outcome measure. After 16 weeks the total NPI score […]

Contribution of relaxation to a psychoeducational intervention program for family carers of persons with Alzheimer’s disease

Unlabelled: Family caregivers of people with Alzheimer’s disease are at high risk of psychological and physical morbidity due to the daily caring experience.; Objectives: to evaluate the impact of a psychoeducational program involving relaxation techniques on caregivers’ burden and mental health status.; Methods: in this prospective study, 50 family caregivers were randomly assigned to one […]

Effects of the TCARE® intervention on caregiver burden and depressive symptoms: preliminary findings from a randomized controlled study

Objectives: We examined the effects of a manualized care management protocol specifically designed for care managers working with caregivers, the Tailored Caregiver Assessment and Referral® (TCARE®) protocol, on caregiver identity discrepancy, burden, and depressive symptoms.; Methods: Preliminary data from a longitudinal, randomized, controlled intervention study with 266 family caregivers served by 52 care managers in […]

Effectiveness of a psychoeducational intervention group program in the reduction of the burden experienced by caregivers of patients with dementia: the EDUCA-II randomized trial

We conducted a multicenter, prospective, evaluator-blinded, 2-arm parallel randomized trial to compare the effectiveness of a group psychoeducational intervention (PIP) with that of standard care in dementia caregivers. The primary outcome was the burden experience evaluated by the Zarit Burden Interview. Secondary outcomes were psychological distress evaluated with the scaled General Health Questionnaire-28 items, and […]

A randomized controlled trial to examine the effectiveness of case management model for community dwelling older persons with mild dementia in Hong Kong

Objective: To evaluate a case management (CM) model for people with mild dementia, whereby resources within the family and in the community were mobilized and optimally used.; Method: Community dwelling psychiatric and geriatrics outpatients with mild dementia were randomized to receive CM by a trained occupational therapist for 4 months (CM group, N = 59) […]

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