Sjögren, Karin, Lindkvist, Marie, Sandman, Per-Olof, Zingmark, Karin, Edvardsson, David

Background: Person-centered care is a multidimensional concept describing good care, especially within aged care and care for people with dementia. Research studies evaluating person-centered care interventions seldom use direct measurement of levels of person-centeredness. Existing scales that measure person-centeredness need further testing. This study evaluated the psychometric properties of the Swedish version of the Person-Centered […]

Schölzel-Dorenbos, Carla J M, Arons, Alexander M M, Wammes, Joost J G, Rikkert, MarcelGMOlde, Krabbe, Paul F M

Background: Index measures for health-related quality of life (HRQoL) quantify the desirability (utility) of a certain health state. The commonly used generic index measure, e.g. EuroQol: EQ-5D, may underestimate relevant areas of specific diseases, resulting in lower validity. Disease-specific index measures on the other hand combine disease-specificity and quantification of perceived quality on several health […]

Schmidt, Reinhold, Baumhackl, Ulf, Berek, Klaus, Brücke, Thomas, Kapeller, Peter, Lechner, Anita, Rainer, Michael, Stögerer, Eva-Maria

We conducted an open, 16-week study on the efficacy of memantine on behavioral disturbances and psychotic symptoms in moderate to moderately severe Alzheimer s disease in daily routine. Fifty-three patients of 20 outpatient centers in Austria were recruited. The Neuropsychiatric Inventory (NPI) was defined as main outcome measure. After 16 weeks the total NPI score […]

Ritchie, L. J., Tuokko, H.

Our objective was to compare the predictive ability of different models of mild cognitive impairment (MCI) as a marker of incipient dementia in a longitudinal population-based Canadian sample. We examined the use of existing, well-documented MCI criteria using data from persons who underwent a clinical examination in the second wave of the Canadian Study of […]

Price, Catherine C., Cunningham, Holly, Coronado, Nicole, Freedland, Alana, Cosentino, Stephanie, Penney, Dana L., Penisi, Alfio, Bowers, Dawn, Okun, Michael S., Libon, David J.

Background: Clock drawing is part of the Montreal Cognitive Assessment (MoCA) test but may have administration and scoring limitations. We assessed (1) the reliability of the MoCA clock criteria relative to a published error scoring approach, (2) whether command-only administration could distinguish dementia from cognitively intact individuals and (3) the value of adding a clock […]

Olin, Jason T., Aarsland, Dag, Meng, Xiangyi

Aims: To investigate the effects of rivastigmine capsule 3-12 mg/day over 24 weeks on activities of daily living (ADLs) in patients with dementia associated with Parkinson’s disease (PDD).; Methods: Post hocanalysis of a prospective, multicenter, randomized, double-blind, placebo-controlled trial in patients with PDD (>or=50 years) randomized to rivastigmine 3-12 mg/day (capsules bid) or placebo over […]

Marioni, Riccardo E, Chatfield, Mark, Brayne, Carol, Matthews, Fiona E.

Background: Previous investigations of test re-test reliability of the Mini-Mental State Examination (MMSE) have used correlations and statistics such as Cronbach’s α to assess consistency. In practice, the MMSE is usually used to group individuals into cognitive states. The reliability of this grouping (state based approach) has not been fully explored.; Methods: MMSE data were […]

Aresi, Anna, Giovagnoli, Anna Rita

This study investigated the neuropsychological hallmarks of posterior cortical atrophy (PCA). Seventeen patients with PCA, 17 patients with probable Alzheimer’s disease (PAD), and 17 healthy age-matched subjects underwent neuropsychological testing for abstract reasoning, visuospatial abilities, memory, language, executive functions, praxes, and attention. The PCA patients were significantly more impaired in visual perception, spatial memory, visual […]