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This database contains 1 studies, archived under the term: "anticholesteremic agents"

Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers

Preclinical and epidemiologic studies suggest a protective effect of statins on Alzheimer disease (AD). Experimental evidence indicates that some statins can cross the blood-brain barrier, alter brain cholesterol metabolism, and may ultimately decrease the production of amyloid-beta (Abeta) peptide. Despite these promising leads, clinical trials have yielded inconsistent results regarding the benefits of statin treatment […]

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