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This database contains 750 studies, archived under the term: "aged, 80 and over"

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Validity and reliability of the Korean version of the AD8 informant interview (K-AD8) in dementia
The Alzheimer disease 8 (AD8) is a brief informant-based measure that distinguishes individuals with very mild dementia and mild cognitive impairment from those with normal cognition. The aim of this study was to establish the validity, reliability, and discriminative properties of the Korean version of the AD8 (K-AD8). Evaluation was made on 155 patient-informant dyads. […]

Malnutrition in community-dwelling adults with dementia (NutriAlz Trial)
Objectives: The objective of this study is to assess the nutritional status, measured by the MNA, in community-dwelling elderly individuals with dementia and to identify clinical risk factors for nutritional risk or malnutrition.; Design: Cross-sectional analysis of a cluster randomized clinical trial (Nutrialz).; Setting: Community-dwelling individuals attending dementia clinics.; Participants: 940 individuals.; Measurements: The clinical […]

Psychotropic drug consumption at admission and discharge of nursing home residents
Objectives: To quantify transitions of residents into or out of nursing homes (NHs) and to describe psychotropic drug prescription at admission and discharge and with regard to dementia diagnosis.; Design: A descriptive, cross-sectional, noninterventional study.; Setting: The setting included 300 NH in France.; Participants: Participants included 2231 NH residents.; Measurements: Participants reported the number, origin, […]

Cognitive assessment of elderly patients in the emergency department: a comparison between standard tools, medical records and physicians’ perception
Introduction: We evaluated the accuracy of physician recognition of cognitive impairment in elderly patients in emergency departments (ED). In particular, we evaluated the accuracy of the subjective impression of the physician on patients’ cognition (a comparison of the information obtained from the responsible physician with the S-IQCODE, a cognitive impairment screening test), and the accuracy […]

Ear therapy and massage therapy in the elderly with dementia: a pilot study
Objective: To assess the impact of massage versus ear acupuncture on behavior and participation in occupational therapy of dementia patients.; Methods: We performed a controlled, randomized longitudinal trial approved by the Bioethics Commission of the University of Extremadura. One hundred twenty elderly subjects with dementia institutionalized in residential homes in Extremadura (Spain) received treatment based […]

A randomized controlled trial of an activity specific exercise program for individuals with Alzheimer disease in long-term care settings
Objective: To determine whether an activity specific exercise program could improve ability to perform basic mobility activities in long-term care residents with Alzheimer disease (AD).; Design: Randomized, controlled, single-blinded clinical trial.; Setting: Residents of 7 long-term care facilities.; Participants: Eighty-two long-term care residents with mild to severe AD.; Intervention: An activity specific exercise program was […]

Patterns of cognitive decline, conversion rates, and predictive validity for 3 models of MCI
Our objective was to compare the predictive ability of different models of mild cognitive impairment (MCI) as a marker of incipient dementia in a longitudinal population-based Canadian sample. We examined the use of existing, well-documented MCI criteria using data from persons who underwent a clinical examination in the second wave of the Canadian Study of […]

Individual music therapy for agitation in dementia: an exploratory randomized controlled trial
Objectives: Agitation in nursing home residents with dementia leads to increase in psychotropic medication, decrease in quality of life, and to patient distress and caregiver burden. Music therapy has previously been found effective in treatment of agitation in dementia care but studies have been methodologically insufficient. The aim of this study was to examine the […]

Prevalence of psychotropic medication use among German and Austrian nursing home residents: a comparison of 3 cohorts
Background: Despite increasing knowledge about the limited effectiveness and severe adverse effects, the prescription rate of psychotropic medications in frail elderly persons remains high. Prescriptions are mainly made to control behavioral and psychological symptoms of dementia, although factors associated with prescriptions are rarely reported. However, such information is a prerequisite to develop intervention programs aiming […]

Vascular care in patients with Alzheimer disease with cerebrovascular lesions slows progression of white matter lesions on MRI: the evaluation of vascular care in Alzheimer’s disease (EVA) study
Background and Purpose: White matter lesions (WMLs) and cerebral infarcts are common findings in Alzheimer disease and may contribute to dementia severity. WMLs and lacunar infarcts may provide a potential target for intervention strategies. This study assessed whether multicomponent vascular care in patients with Alzheimer disease with cerebrovascular lesions slows progression of WMLs and prevents […]

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