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This database contains 62 studies, archived under the term: "Treatment/prevention of co-morbidities or additional risks"

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More insight into the concept of apathy: a multidisciplinary depression management program has different effects on depressive symptoms and apathy in nursing homes
Background: Apathy is common in nursing home (NH) residents and it overlaps with depression. This study examines the effects of a multidisciplinary depression program on apathy and depressive motivational and mood symptoms.; Methods: Secondary analyses of a stepped-wedge cluster-randomized controlled trial were conducted with six measurements. Sixteen dementia NH units and 17 somatic units were […]

A structural multidisciplinary approach to depression management in nursing-home residents: a multicentre, stepped-wedge cluster-randomised trial
Background: Depression in nursing-home residents is often under-recognised. We aimed to establish the effectiveness of a structural approach to its management.; Methods: Between May 15, 2009, and April 30, 2011, we undertook a multicentre, stepped-wedge cluster-randomised trial in four provinces of the Netherlands. A network of nursing homes was invited to enrol one dementia and […]

Effects of a multimodal exercise program on balance, functional mobility and fall risk in older adults with cognitive impairment: a randomized controlled single-blind study
Background: Exercise programs have important role in prevention of falls, but to date, there are conflicting findings about the effects of exercise programs on balance, functional performance and fall risk among cognitively impaired older adults. AIM. To investigate the effects of a multimodal exercise program on static and dynamic balance, and risk of falls in […]

Video game play (Dance Dance Revolution) as a potential exercise therapy in Huntington’s disease: a controlled clinical trial
Objective: To investigate the feasibility, acceptability, and safety of a supervised video game exercise program administered via Dance Dance Revolution in individuals with Huntington’s disease.; Design: A cross-over, controlled, single-blinded, six-week trial.; Setting: Home-based.; Participants: Eighteen ambulatory individuals with Huntington’s disease (seven male, mean age 50.7 SD 14.7).; Interventions: Participants played the Dance Dance Revolution […]

Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial
Objective: To determine whether a systematic approach to the treatment of pain can reduce agitation in people with moderate to severe dementia living in nursing homes.; Design: Cluster randomised controlled trial.; Setting: 60 clusters (single independent nursing home units) in 18 nursing homes within five municipalities of western Norway.; Participants: 352 residents with moderate to […]

Efficacy of pain treatment on mood syndrome in patients with dementia: A randomized clinical trial
Background: Depression is common in nursing home (NH) patients with dementia, and often clustered with anxiety and other mood symptoms. An association between pain and depressive symptoms has been reported, but the impact of pain management on depression and other mood symptoms has not been investigated. Objective: Secondary analyses of a cluster randomized clinical trial […]

A prospective field study for sensor-based identification of fall risk in older people with dementia
Objective: Aim of this study was to make a fall prognosis in a cohort of older people with dementia in short-term (2 month), mid-term (4 month) and long-term (8 month) intervals using accelerometry during the subjects’ everyday life. Methods: The study was designed as a longitudinal cohort study. The subjects were recruited from a nursing […]

The FABS trial: a randomised control trial of the effects of a 6-month physical activity intervention on adherence and long-term physical activity and self-efficacy in older adults with memory complaints
Objective: The aim of this study is to assess in older adults with memory complaints, the effects of a 6-month home-based physical activity (PA) intervention on short-term adherence, short and long-term self-efficacy and the predictors of adherence.; Methods: Participants with memory complaints with or without mild cognitive impairment (MCI) were recruited from Perth, Western Australia […]

The impact of group music therapy on depression and cognition in elderly persons with dementia: a randomized controlled study
Objective: The aims of this study were to determine the effectiveness of group music therapy for improving depression and delaying the deterioration of cognitive functions in elderly persons with dementia.; Method: The study had a prospective, parallel-group design with permuted-block randomization. Older persons with dementia (N = 104) were randomly assigned to the experimental or […]

Clinical outcomes and complications of enteral nutrition among older adults
Aim: Several reviews or clinical trials published in the last years have not demonstrated that tube feeding can improve outcomes, including inhalation pneumonia, survival, pressure sores. Further, high rate of risks are recognized. Therefore, this practice should be discouraged for severely demented patients. The aim of this study was to assess the validity of these […]

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