Wesson, Jacqueline, Clemson, Lindy, Brodaty, Henry, Lord, Stephen, Taylor, Morag, Gitlin, Laura, Close, Jacqueline

Background: People with dementia have a disproportionately high rate of falls and fractures and poorer outcomes, yet there is currently no evidence to guide falls prevention in this population.; Methods: A randomised trial design was used to test feasibility of study components and acceptability of a home hazard reduction and balance and strength exercise fall […]

van de Ven, Geertje, Draskovic, Irena, van Herpen, Elke, Koopmans, Raymond T. C. M., Donders, Rogier, Zuidema, Sytse U., Adang, Eddy M. M., Vernooij-Dassen, Myrra J. F. J.

Background: Dementia-care mapping (DCM) is a cyclic intervention aiming at reducing neuropsychiatric symptoms in people with dementia in nursing homes. Alongside an 18-month cluster-randomized controlled trial in which we studied the effectiveness of DCM on residents and staff outcomes, we investigated differences in costs of care between DCM and usual care in nursing homes. Methods: […]

Sato, Y., Honda, Y., Iwamoto, J., Amano, N.

Objectives: Minodronate is a nitrogen-containing bisphosphonate that is commercially available for the treatment of osteoporosis in Japan. Preclinical studies demonstrated that minodronate is at least 10 times more potent than alendronate in inhibiting bone resorption in vivo. A high incidence of fractures, particularly of the hip, represents an important problem in Alzheimer disease (AD) patients […]

Pitkälä, Kaisu H., Pöysti, Minna M., Laakkonen, Marja-Liisa, Tilvis, Reijo S., Savikko, Niina, Kautiainen, Hannu, Strandberg, Timo E.

Importance: Few rigorous clinical trials have investigated the effectiveness of exercise on the physical functioning of patients with Alzheimer disease (AD).; Objectives: To investigate the effects of intense and long-term exercise on the physical functioning and mobility of home-dwelling patients with AD and to explore its effects on the use and costs of health and […]

Kovács, E., Sztruhár Jónásné, I., Karóczi, C. K., Korpos, A., Gondos, T.

Background: Exercise programs have important role in prevention of falls, but to date, there are conflicting findings about the effects of exercise programs on balance, functional performance and fall risk among cognitively impaired older adults. AIM. To investigate the effects of a multimodal exercise program on static and dynamic balance, and risk of falls in […]

Gietzelt, Matthias, Feldwieser, Florian, Gövercin, Mehmet, Steinhagen-Thiessen, Elisabeth, Marschollek, Michael

Objective: Aim of this study was to make a fall prognosis in a cohort of older people with dementia in short-term (2 month), mid-term (4 month) and long-term (8 month) intervals using accelerometry during the subjects’ everyday life. Methods: The study was designed as a longitudinal cohort study. The subjects were recruited from a nursing […]

Brožová, Hana, Štochl, Jan, Klempíř, Jiří, Kucharík, Martin, Růžička, Evžen, Roth, Jan

Falls are a common complication in Huntington’s disease (HD) and detection of postural instability (PI) may be useful for identifying patients who are at risk of falls. The aim of our study was to find the most sensitive clinical test for PI in patients with HD and to correlate PI with the other symptoms. 20 […]