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Ingestion of Chlorella reduced the oxidation of erythrocyte membrane lipids in senior Japanese subjects
Miyazawa, Taiki,
Nakagawa, Kiyotaka,
Takekoshi, Hideo,
Higuchi, Ohki,
Kato, Shunji,
Kondo, Momoko,
Kimura, Fumiko,
Miyazawa, Teruo
...2 months Chlorella supplementation (8 g Chlorella/day/person; equivalent to 22.9 mg lutein/day/person) on PLOOH and carotenoid concentrations in erythrocytes as well as plasma of 12 normal senior subjects. After 1...
The preclinical Alzheimer cognitive composite: Measuring amyloid-related decline
Donohue, Michael C.,
Sperling, Reisa A.,
Salmon, David P.,
Rentz, Dorene M.,
Raman, Rema,
Thomas, Ronald G.,
Weiner, Michael,
Aisen, Paul S
...decline than did Aβ-negative participants with regard to the ADCS-PACC score at 24 months (mean [SE] difference, -1.239 [0.522] [95% CI, -2.263 to -0.215]; P = .02). In AIBL, the...
The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial
Ballard, Clive,
Hanney, Maria Luisa,
Theodoulou, Megan,
Douglas, Simon,
McShane, Rupert,
Kossakowski, Katja,
Gill, Randeep,
Juszczak, Edmund,
Yu, Ly-Mee,
Jacoby, Robin
...continue with their antipsychotic treatment (thioridazine, chlorpromazine, haloperidol, trifluoperazine, or risperidone) for 12 months or to switch their medication to an oral placebo. The primary outcome was mortality at 12...
Effects on transthyretin in plasma and cerebrospinal fluid by DHA-rich n – 3 fatty acid supplementation in patients with Alzheimer’s disease: the OmegAD study
Faxén-Irving, Gerd,
Freund-Levi, Yvonne,
Eriksdotter-Jönhagen, Maria,
Basun, Hans,
Hjorth, Erik,
Palmblad, Jan,
Vedin, Inger,
Cederholm, Tommy,
Wahlund, Lars-Olof
...and 0.6 g EPA (n – 3/n – 3 group) or placebo (placebo/n – 3 group) during 6 months. After 6 months, all patients received n – 3 FA for...
The long-term effect of group living homes versus regular nursing homes for people with dementia on psychological distress of informal caregivers
Smit, Dieneke,
te Boekhorst, Selma,
de Lange, Jacomine,
Depla, Marja F.I.A.,
Eefsting, Jan A.,
Pot, Anne-Margriet
...of GLH (N = 37) and NH residents (N = 49) were studied at the time of admission, 6 months thereafter, and approximately 24 months after admission. Repeated measures of...
Clinical trial of an inhibitor of RAGE-Aβ interactions in Alzheimer disease
Galasko, D.,
Bell, J.,
Mancuso, J. Y.,
Kupiec, J. W.,
Sabbagh, M. N.,
van Dyck, C.,
Thomas, R. G.,
Aisen, P. S.
...(high dose); 15 mg/day × 6 days, then 5 mg daily (low dose); or placebo, for 18 months. Clinical and laboratory measures were used to evaluate safety and tolerability. The...
Medication adherence in patients with dementia: An Austrian cohort study
Haider, Bernhard,
Schmidt, Reinhold,
Schweiger, Christine,
Forstner, Thomas,
Labek, Anna,
Lampl, Christian
...= 2808). After 6 and 12 months on therapy, 5376 (34.0%) and 9243 (58.5%) patients stopped the initially prescribed antidementia therapy; after 12 months the highest discontinuation rate was seen...