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Ingestion of Chlorella reduced the oxidation of erythrocyte membrane lipids in senior Japanese subjects
Miyazawa, Taiki,
Nakagawa, Kiyotaka,
Takekoshi, Hideo,
Higuchi, Ohki,
Kato, Shunji,
Kondo, Momoko,
Kimura, Fumiko,
Miyazawa, Teruo
...2 months Chlorella supplementation (8 g Chlorella/day/person; equivalent to 22.9 mg lutein/day/person) on PLOOH and carotenoid concentrations in erythrocytes as well as plasma of 12 normal senior subjects. After 1...
Clinical outcomes and complications of enteral nutrition among older adults
Attanasio, A.,
Bedin, M.,
Stocco, S.,
Negrin, V.,
Biancon, A.,
Cecchetto, G.,
Tagliapietra, M.
...distinctive aspect of this study concerns the fact that all patients with tube feeding were followed at home, in hospital, in nursing home by the same NT. The team controls...
“Dementia-friendly hospitals: care not crisis”: an educational program designed to improve the care of the hospitalized patient with dementia
Galvin, James E.,
Kuntemeier, Barbara,
Al-Hammadi, Noor,
Germino, Jessica,
Murphy-White, Maggie,
McGillick, Janis
...Background: Approximately 3.2 million hospital stays annually involve a person with dementia, leading to higher costs, longer lengths of stay, and poorer outcomes. Older adults with dementia are vulnerable...
Clinical trial of an inhibitor of RAGE-Aβ interactions in Alzheimer disease
Galasko, D.,
Bell, J.,
Mancuso, J. Y.,
Kupiec, J. W.,
Sabbagh, M. N.,
van Dyck, C.,
Thomas, R. G.,
Aisen, P. S.
...(high dose); 15 mg/day × 6 days, then 5 mg daily (low dose); or placebo, for 18 months. Clinical and laboratory measures were used to evaluate safety and tolerability. The...
Effects on transthyretin in plasma and cerebrospinal fluid by DHA-rich n – 3 fatty acid supplementation in patients with Alzheimer’s disease: the OmegAD study
Faxén-Irving, Gerd,
Freund-Levi, Yvonne,
Eriksdotter-Jönhagen, Maria,
Basun, Hans,
Hjorth, Erik,
Palmblad, Jan,
Vedin, Inger,
Cederholm, Tommy,
Wahlund, Lars-Olof
...and 0.6 g EPA (n – 3/n – 3 group) or placebo (placebo/n – 3 group) during 6 months. After 6 months, all patients received n – 3 FA for...
The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial
Ballard, Clive,
Hanney, Maria Luisa,
Theodoulou, Megan,
Douglas, Simon,
McShane, Rupert,
Kossakowski, Katja,
Gill, Randeep,
Juszczak, Edmund,
Yu, Ly-Mee,
Jacoby, Robin
...continue with their antipsychotic treatment (thioridazine, chlorpromazine, haloperidol, trifluoperazine, or risperidone) for 12 months or to switch their medication to an oral placebo. The primary outcome was mortality at 12...
The preclinical Alzheimer cognitive composite: Measuring amyloid-related decline
Donohue, Michael C.,
Sperling, Reisa A.,
Salmon, David P.,
Rentz, Dorene M.,
Raman, Rema,
Thomas, Ronald G.,
Weiner, Michael,
Aisen, Paul S
...decline than did Aβ-negative participants with regard to the ADCS-PACC score at 24 months (mean [SE] difference, -1.239 [0.522] [95% CI, -2.263 to -0.215]; P = .02). In AIBL, the...
Effects of centrally acting angiotensin converting enzyme inhibitors on functional decline in patients with Alzheimer’s disease
O'Caoimh, Rónán,
Healy, Liam,
Gao, Yang,
Svendrovski, Anton,
Kerins, David M.,
Eustace, Joseph,
Kehoe, Patrick Gavin,
Guyatt, Gordon,
Molloy, D. William
...Background: Centrally acting angiotensin converting enzyme inhibitors (CACE-Is) are associated with reduced rates of cognitive decline in patients with dementia. CACE-Is may also improve exercise tolerance in functionally impaired...
Medication adherence in patients with dementia: An Austrian cohort study
Haider, Bernhard,
Schmidt, Reinhold,
Schweiger, Christine,
Forstner, Thomas,
Labek, Anna,
Lampl, Christian
...Study outcome measures were discontinuation, switching, number of days on therapy, Medication-Possession-Ratio, and compliance. A total of 15,809 patients (mean age: 79.9 y, female: 67.3%) met the study’s inclusion criteria....