Cukierman-Yaffe, Tali, Gerstein, Hertzel C., Williamson, Jeff D., Lazar, Ronald M., Lovato, Laura, Miller, Michael E., Coker, Laura H., Murray, Anne, Sullivan, Mark D., Marcovina, Santica M., Launer, Lenore J.

Objective: Diabetes is associated with cognitive decline and dementia. However, the relationship between the degree of hyperglycemia and cognitive status remains unclear. This was explored using baseline cognitive measures collected in the ongoing Memory in Diabetes (MIND) substudy of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.; Research Design and Methods: The relationship […]

Mühlau, M., Wohlschläger, A. M., Gaser, C., Valet, M., Weindl, A., Nunnemann, S., Peinemann, A., Etgen, T., Ilg, R.

Background and Purpose: Voxel-based morphometry (VBM) has proved a powerful method to detect subtle changes of gray matter (GM) at the group level but the role of VBM for the detection of GM changes in single subjects, especially in those with suspected neurodegenerative disorder, remains uncertain. Here, we performed single subject analyses in 22 patients […]

Chiu, Y. C., Huang, C. Y., Kolanowski, A. M., Huang, H. L., Shyu, Y. L., Lee, S. H., Lin, C. R., Hsu, W. C.

BACKGROUND: People with cognitive impairment have been shown to engage in few structured activities. During periods of unoccupied time or boredom, these patients most likely manifest neuropsychiatric symptoms. OBJECTIVE: The purposes of this study were to (1) describe the leisure-activity indicators (variety in leisure activities, appraisal of each activity’s restorative function, and leisure dysfunction, i.e. […]

Beking, Kristopher, Vieira, Amandio

Objective: Dietary flavonoids and their metabolites may have neuroprotective effects against age-associated neurodegenerative disorders such as Alzheimer’s and related dementias (dementia). There is a lack of population studies, however, on correlations between flavonoid intake and dementia. The main objective of the present study was to analyse such a relationship at a large-scale population level.; Design: […]