This site uses cookies to measure how you use the website so it can be updated and improved based on your needs and also uses cookies to help remember the notifications you’ve seen, like this one, so that we don’t show them to you again. If you could also tell us a little bit about yourself, this information will help us understand how we can support you better and make this site even easier for you to use and navigate.

Transdermal is better than oral: observational research of the satisfaction of caregivers of patients with Alzheimer’s disease treated with rivastigmine


Boada, Mercè, Arranz, Francisco Javier


Dementia And Geriatric Cognitive Disorders, Volume: 35, No.: 1-2, Pages.: 23-33

Year of Publication



Background and Aims: Poor adherence to anti-dementia drugs is common among patients with Alzheimer’s disease. This study evaluated whether caregivers were more satisfied with, and patients more adherent to, transdermal rivastigmine than oral rivastigmine.; Methods: Neurologists, psychiatrists and geriatricians collected sociodemographic and clinical data from 1,078 patients and administered the Treatment Satisfaction with Medicines (SATMED-Q) and the Morisky-Green questionnaires to their caregivers at outpatient consultations.; Results: Satisfaction reported was greater with transdermal than oral rivastigmine: mean ± SD of the total SATMED-Q score, 72.5 ± 14.1 vs. 65.2 ± 12.5, p < 0.001. The proportion of adherent patients was greater with transdermal than with oral rivastigmine (65.0 vs. 41.4%, p < 0.001). Satisfaction, in turn, was significantly greater in adherent cases than in nonadherent cases.; Conclusions: Facilitating the administration of anti-dementia drugs would improve adherence.; Copyright © 2013 S. Karger AG, Basel.

Bibtex Citation

@article{Boada_2013, doi = {10.1159/000345989}, url = {}, year = 2013, publisher = {S. Karger {AG}}, volume = {35}, number = {1-2}, pages = {23--33}, author = {Merc{`{e}} Boada and Francisco Javier Arranz}, title = {Transdermal Is Better than Oral: Observational Research of the Satisfaction of Caregivers of Patients with Alzheimer’s Disease Treated with Rivastigmine}, journal = {Dementia and Geriatric Cognitive Disorders} }


adherence, administration & dosage, administration cutaneous, administration oral, aged, aged, 80 and over, alzheimer disease, and, caregivers, crosssectional studies, data interpretation statistical, drug therapy, educational status, female, humans, male, marital status, medication, middle aged, neuroprotective agents, neuropsychological tests, oral, patient compliance, patient satisfaction, phenylcarbamates, psychology, questionnaires, rivastigmine, therapeutic use, transdermal

Countries of Study


Types of Dementia

Dementia (general / unspecified)

Types of Study

Cohort Study

Type of Outcomes

Other, Satisfaction with care/services

Type of Interventions

Pharmaceutical Interventions

Pharmaceutical Interventions

Anti-Alzheimer medications, e.g.: donezepil, galantamine, rivastigmine, memantime