This site uses cookies to measure how you use the website so it can be updated and improved based on your needs and also uses cookies to help remember the notifications you’ve seen, like this one, so that we don’t show them to you again. If you could also tell us a little bit about yourself, this information will help us understand how we can support you better and make this site even easier for you to use and navigate.

Normal pressure hydrocephalus or neuroborreliosis?

Authors

Aboul-Enein, Fahmy, Kristoferitsch, Wolfgang

Journal

Wiener Medizinische Wochenschrift (1946), Volume: 159, No.: 1-2, Pages.: 58-61

Year of Publication

2009

Abstract

Background: An 80-year-old woman presented with progressive cognitive decline and with a 6-month history of gait ataxia. Brain MRI depicted enlarged ventricles and periventricular lesions. Clinical improvement after CSF spinal tap test suggested a normal pressure hydrocephalus syndrome. But CSF pleocytosis with activated lymphocytes and plasma cells and intrathecal Borrelia burgdorferi specific antibody production led to the diagnosis of active Lyme neuroborreliosis. Clinical symptoms of NPH resolved after a course of ceftriaxone.; Methods: Neurological examination, MMSE, brain MRI, lumbar puncture, spinal tap test.; Results: Dementia due Borrelia burgdorferi infection with chronic meningitis was reversible after treatment with iv.2 g ceftriaxone per day for 4 weeks.; Conclusions: Rare but treatable dementias must be diagnosed promptly to slow down or even reverse cognitive decline.;

Bibtex Citation

@article{Aboul_Enein_2009, doi = {10.1007/s10354-008-0581-4}, url = {http://dx.doi.org/10.1007/s10354-008-0581-4}, year = 2009, month = {jan}, publisher = {Springer Science $mathplus$ Business Media}, volume = {159}, number = {1-2}, pages = {58--61}, author = {Fahmy Aboul-Enein and Wolfgang Kristoferitsch}, title = {Normal pressure hydrocephalus or neuroborreliosis?}, journal = {Wiener Medizinische Wochenschrift} }

Keywords

administration & dosage, aged, 80 and over, anti-bacterial agents, antibiotics, ceftriaxone, cerebrospinal fluid, dementia, diagnosis, diagnosis, differential, drug therapy, etiology, female, gait ataxia, humans, hydrocephalus, normal pressure, lyme neuroborreliosis*, magnetic resonance imaging, mental status schedule, neurologic examination, therapeutic use, time factors, treatment outcome

Countries of Study

Austria

Types of Study

Other

Type of Outcomes

Cognition

Type of Interventions

Pharmaceutical Interventions

Pharmaceutical Interventions

Other