This site uses cookies to measure how you use the website so it can be updated and improved based on your needs and also uses cookies to help remember the notifications you’ve seen, like this one, so that we don’t show them to you again. If you could also tell us a little bit about yourself, this information will help us understand how we can support you better and make this site even easier for you to use and navigate.

Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia


Wang, L. P., Zhang, X. Y., Liu, N., Ma, Z. Z., Fang, D. S.


Genetics And Molecular Research: GMR, Volume: 14, No.: 2, Pages.: 4896-4902

Year of Publication



The aim of this study was to investigate the clinical effect of western medicine therapy assisted by Ginkgo biloba tablets (GBT) in patients with vascular cognitive impairment with no dementia (VCIND). Eighty patients with VCIND were randomly divided into two groups: the conventional treatment group (control group) and the combined treatment group. The conventional treatment group was provided with anti-platelet aggregation conventional treatment. In this group, 75 mg aspirin was given three times a day for 3 months, whereas the combined treatment group was given 19.2 mg GBT three times a day for 3 months along with conventional anti-platelet aggregation treatment. Montreal cognitive assessment (MoCA) and transcranial Doppler ultrasonography were used to observe changes in cognitive ability and cerebral blood flow in patients with VCIND before and after treatment in the two groups. After 3 months of treatment, the MoCA scores of execution, attention, abstraction, delayed memory, and orientation were significantly increased in the combined treatment group compared with those before treatment and those in the control group after treatment. In addition, the blood flow velocity of the anterior cerebral artery was significantly increased in the combined treatment group. GBT can improve the therapeutic efficacy, cognitive ability, and cerebral blood flow supply of patients with VCIND.;

Bibtex Citation

@article{Wang_2015, doi = {10.4238/2015.may.11.22}, url = {}, year = 2015, publisher = {Genetics and Molecular Research}, volume = {14}, number = {2}, pages = {4896--4902}, author = {L.P. Wang and X.Y. Zhang and N. Liu and Z.Z. Ma and D.S. Fang}, title = {Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia}, journal = {Genetics and Molecular Research} }


administration & dosage, aged, aspirin, biloba, blood supply, cerebellum, chemistry, cognition disorders, dementia, drug effects, drug therapy, drugs chinese herbal, female, ginkgo, ginkgo biloba, humans, male, medicine chinese traditional, middle aged, pathology, physiopathology, plant extracts, ultrasonography doppler transcranial, vascular diseases

Countries of Study


Types of Dementia

Mild Cognitive Impairment (MCI)

Types of Study

Randomised Controlled Trial

Type of Outcomes


Type of Interventions

Pharmaceutical Interventions

Pharmaceutical Interventions

Herbal remedies, vitamins, dietary supplements, Other