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This database contains 33 studies, archived under the term: "Behavioural Therapies"

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Efficacy of nonpharmacologic interventions for agitation in advanced dementia: a randomized, placebo-controlled trial

Background: A randomized, placebo-controlled clinical trial was undertaken to determine the efficacy of nonpharmacologic individualized interventions (individualized to address unmet needs such as boredom or pain) in decreasing agitation in persons with dementia.; Method: Agitated nursing home residents with advanced dementia (from 9 nursing homes in 5 locations in Maryland, United States) were randomized into […]

Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT)

Background: Preliminary evidence suggests that goal-oriented cognitive rehabilitation (CR) may be a clinically effective intervention for people with early-stage Alzheimer’s disease, vascular or mixed dementia and their carers. This study aims to establish whether CR is a clinically effective and cost-effective intervention for people with early-stage dementia and their carers.; Methods/design: In this multi-centre, single-blind […]

Methodological issues in the non pharmacological treatment of BPSD in nursing home–the TNM study

Behavioural and psychological symptoms of dementia (BPSD) such as agitation, aggressiveness, oppositional behaviour and psychotic symptoms are often reported by caregivers and staff members in institutions for the elderly. Taking into account the limited efficacy and the importance of side effects observed with psychotropic agents, the majority of existing guideline underlines the importance of non-pharmacological […]

Home-delivered problem adaptation therapy (PATH) for depressed, cognitively impaired, disabled elders: A preliminary study

Objectives: This preliminary study examines the efficacy of 12-week home-delivered problem adaptation therapy (PATH) versus home-delivered supportive therapy (ST) in reducing depression and disability in 30 depressed, cognitively impaired, disabled older adults.; Design: A 12-week randomized clinical trial. Research assistants were unaware of the participants’ randomization status. Assessments were conducted at baseline, 6 weeks, and […]

Non-pharmacological management of behavioural symptoms in nursing homes

Background: Behavioural and psychological symptoms of dementia (BPSD) are often reported in institutions for the elderly.; Objective: To evaluate the effectiveness of a staff education intervention to manage BPSD in older people with a diagnosis of dementia.; Methods: The trial was conducted in 16 nursing homes; 306 patients with a diagnosis of dementia and presenting […]

Errorless practice as a possible adjuvant to donepezil in Alzheimer’s disease

Six individuals with probable Alzheimer’s disease (AD) participated in a phase 1 study employing a repeated measures, parallel baseline design testing the hypothesis that error-free experience during word production practice combined with an acetyl cholinesterase inhibitor would improve confrontation naming ability. While acetyl cholinesterase inhibitors are safe and delay cognition decline associated with AD, improvement […]

The Danish Alzheimer intervention study: rationale, study design and baseline characteristics of the cohort

Background: There is a lack of appropriately designed trials investigating the efficacy of psychosocial interventions for patients with mild dementia and their family caregivers. This paper reports the rationale and design of the Danish Alzheimer Disease Intervention Study and baseline characteristics of the cohort.; Methods: The study was a 1-year multicentre randomized controlled rater-blinded trial […]

A randomized controlled trial for an individualized positive psychosocial intervention for the affective and behavioral symptoms of dementia in nursing home residents

Objectives: This randomized controlled study tested the effectiveness of individualized activities, led by certified nursing assistants (CNAs), to increase positive and reduce negative affect and behavior among nursing home residents with dementia. Method: Nursing home residents with mild to advanced dementia (N = 180) were randomly assigned to usual care (UC, n = 93) or […]

A randomized crossover trial to study the effect of personalized, one-to-one interaction using Montessori-based activities on agitation, affect, and engagement in nursing home residents with Dementia

Background: Increasingly more attention has been paid to non-pharmacological interventions as treatment of agitated behaviors that accompany dementia. The aim of the current study is to test if personalized one-to-one interaction activities based on Montessori principles will improve agitation, affect, and engagement more than a relevant control condition.; Methods: We conducted a randomized crossover trial […]

The Peaceful Mind program: A pilot test of a cognitive–behavioral therapy–based intervention for anxious patients with Dementia

Objectives: To assess feasibility and to conduct a preliminary evaluation of outcomes following Peaceful Mind, a cognitive-behavioral therapy-based intervention for anxiety in dementia, relative to usual care. Design: Pilot randomized controlled trial including assessments at baseline and 3 and 6 months. Setting: Houston, TX. Participants: Thirty-two outpatients diagnosed with mild (47%) or moderate (53%) dementia […]

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