Quinn, Catherine, Anderson, Daniel, Toms, Gill, Whitaker, Rhiannon, Edwards, Rhiannon Tudor, Jones, Carys, Clare, Linda

Background: The possibility of living well with a long-term condition has been identified as centrally relevant to the needs of people living with dementia. Growing numbers of people with early-stage dementia are contributing accounts that emphasise the benefits of actively engaging in managing the condition. Self-management interventions share the common objectives of educating about the […]

Subramaniam, Ponnusamy, Woods, Bob, Whitaker, Chris

Objectives: To evaluate the effect of different pathways for developing a life story book (LSB) for people with dementia.; Method: Preliminary randomised control trial; 23 people with dementia in care homes (mean age 86) randomly assigned to receive either 12 individual life review sessions and co-creating a LSB or a personal LSB created by their […]

Marioni, Riccardo E, Chatfield, Mark, Brayne, Carol, Matthews, Fiona E.

Background: Previous investigations of test re-test reliability of the Mini-Mental State Examination (MMSE) have used correlations and statistics such as Cronbach’s α to assess consistency. In practice, the MMSE is usually used to group individuals into cognitive states. The reliability of this grouping (state based approach) has not been fully explored.; Methods: MMSE data were […]

Khalil, H., Quinn, L., van Deursen, R., Dawes, H., Playle, R., Rosser, A., Busse, M.

Objective: The aim of this study was to explore feasibility, safety and outcome of an exercise intervention in people with Huntington’s disease.; Design: A randomized controlled pilot trial.; Setting: A home-based exercise programme.; Subjects: A total of 25 subjects with early to mid-stage Huntington’s disease.; Intervention: Subjects were randomly allocated to either an exercise intervention […]

Hippisley-Cox, J., Coupland, C.

Objective: To quantify the unintended effects of statins according to type, dose, and duration of use.; Design: Prospective open cohort study using routinely collected data.; Setting: 368 general practices in England and Wales supplying data to the QResearch database.; Participants: 2 004 692 patients aged 30-84 years of whom 225 922 (10.7%) were new users […]