Iliffe, Steve, Koch, Tamar, Jain, Priya, Lefford, Frances, Wong, Geoffrey, Warner, Alex, Wilcock, Jane

Background: Dementia syndromes are under-diagnosed and under-treated in primary care. Earlier recognition of and response to dementia syndrome is likely to enhance the quality of life of people with dementia, but general practitioners consistently report limited skills and confidence in diagnosis and management of this condition. Changing clinical practice is difficult, and the challenge for […]

Volandes, Angelo E., Paasche-Orlow, Michael K., Barry, Michael J., Gillick, Muriel R., Minaker, Kenneth L., Chang, Yuchiao, Cook, E. Francis, Abbo, Elmer D., El-Jawahri, Areej, Mitchell, Susan L.

Objective: To evaluate the effect of a video decision support tool on the preferences for future medical care in older people if they develop advanced dementia, and the stability of those preferences after six weeks.; Design: Randomised controlled trial conducted between 1 September 2007 and 30 May 2008. Setting Four primary care clinics (two geriatric […]

Volandes, Angelo E., Mitchell, Susan L., Gillick, Muriel R., Chang, Yuchiao, Paasche-Orlow, Michael K.

Introduction: When patients are unable to make important end-of-life decisions, doctors ask surrogate decision makers to provide insight into patients’ preferences. Unfortunately, multiple studies have shown that surrogates’ knowledge of patient preferences is poor. We hypothesized that a video decision tool would improve concordance between patients and their surrogates for end-of-life preferences.; Objective: To compare […]

Pyo, Geunyeong, Ala, Tom, Kyrouac, Gregory A., Verhulst, Steven J.

The purpose of the present study was to investigate the validity of the Working Group’s Autobiographical Memory Test as a dementia screening tool for individuals with moderate to severe intellectual disabilities (ID). Twenty-one participants with Dementia of Alzheimer’s Type (DAT) and moderate to severe ID and 42 controls with similar levels of ID were tested. […]

Liu, Yawu, Mattila, Jussi, Ruiz, Miguel Ángel Muñoz, Paajanen, Teemu, Koikkalainen, Juha, van Gils, Mark, Herukka, Sanna-Kaisa, Waldemar, Gunhild, Lötjönen, Jyrki, Soininen, Hilkka

Purpose: To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA) on MRI and CSF biomarkers.; Methods: Altogether 391 MCI cases (158 […]