Makizako, Hyuma, Doi, Takehiko, Shimada, Hiroyuki, Yoshida, Daisuke, Tsutsumimoto, Kota, Uemura, Kazuki, Suzuki, Takao

Background and Aims: There has been much interest in exercise interventions as a primary behavioral prevention strategy against cognitive decline. The aim of this study was to evaluate the effect of a multicomponent exercise program on physical and dual-task performances in community-dwelling older adults with amnestic mild cognitive impairment (aMCI).; Methods: Fifty older adults (23 […]

Flöel, Agnes, Suttorp, Wiebke, Kohl, Oliver, Kürten, Julia, Lohmann, Hubertus, Breitenstein, Caterina, Knecht, Stefan

Remembering the location of objects, an integral part of everyday life, is known to decline with advancing age and early in the course of neurodegenerative dementia. Here, we aimed to test if object-location learning and its retention could be modified by noninvasive brain stimulation. In a group of 20 elderly (mean age 62.1 years) right-handed […]

Moro, V., Condoleo, M. T., Sala, F., Pernigo, S., Moretto, G., Gambina, G.

Nowadays, preventing the effects of mental decline is an international priority, but there is little research into cognitive training in mild cognitive impairment (MCI). We present the results of a program aimed at teaching memory strategies and improving metacognitive abilities. This was associated with training to ameliorate caregivers’ assistance. Two groups (A and B) were […]

Rochester, Lynn, Burn, David J., Woods, Gillian, Godwin, Jon, Nieuwboer, Alice

Gait and balance problems resulting from Parkinson’s disease (PD) are more common in people with PD and dementia (PDD), yet, it is unknown whether the benefits of cueing therapy for mobility generalize to them. We aimed to determine the feasibility and effectiveness of auditory cues to improve gait in PD and cognitive impairment (PD-CI). Nine […]

Wilkins, Consuelo H., Roe, Catherine M., Morris, John C.

The aim was to develop a brief physical performance assessment tool that can be reliably used to detect physical impairment in older adults with and without mild dementia. Scores on the 9-item physical performance test (PPT) from non-demented participants were used to develop and validate the 4-item mini-PPT. The validated mini-PPT was then used to […]

Quinn, L., Debono, K., Dawes, H., Rosser, A. E., Nemeth, A. H., Rickards, H., Tabrizi, S. J., Quarrell, O., Trender-Gerhard, I., Kelson, M. J., Townson, J., Busse, M.

Background: Task-specific training may be a suitable intervention to address mobility limitations in people with Huntington disease (HD).; Objective: The aim of this study was to assess the feasibility and safety of goal-directed, task-specific mobility training for individuals with mid-stage HD.; Design: This study was a randomized, blinded, feasibility trial; participants were randomly assigned to […]