Zellner, Maria, Babeluk, Rita, Jakobsen, Lene H., Gerner, Christopher, Umlauf, Ellen, Volf, Ivo, Roth, Erich, Kondrup, Jens

Studies investigating the impact of high meat intake on cognition have yielded contradictory results as some show improved cognitive performance, whereas others report an increase of risk factors for dementia. However, few studies were designed to directly assess the effect of a high protein (HP) diet on both cognitive performance and corresponding biochemical parameters. A […]

Bakker, Arnold, Krauss, Gregory L., Albert, Marilyn S., Speck, Caroline L., Jones, Lauren R., Stark, Craig E., Yassa, Michael A., Bassett, Susan S., Shelton, Amy L., Gallagher, Michela

Elevated hippocampal activation is observed in conditions that confer risk for Alzheimer’s disease, including amnestic mild cognitive impairment (aMCI). Studies in relevant animal models have indicated that overactivity in selective hippocampal circuits contributes to cognitive impairment. Here, we tested the effect of reducing hippocampal activation in aMCI. Under placebo treatment, hippocampal activation in the dentate […]

Gagnon, Lyssa G., Belleville, Sylvie

This study evaluated the efficacy of a cognitive intervention for attentional control in older adults with mild cognitive impairment (MCI) with an executive deficit. It also sought to verify if the benefits of training generalised to primary and secondary outcome measures. Participants (n = 24) were randomly assigned to a training programme or active control […]

Feldman, Howard H., Pirttila, Tuula, Dartigues, Jean-François, Everitt, Brian, Van Baelen, Bart, Schwalen, Susanne, Kavanagh, Shane

Objective: This study evaluated patient and treatment (galantamine and other acetylcholinesterase inhibitors (AChEIs)) factors associated with the time until nursing home placement (NHP) in patients with Alzheimer’s disease (AD) with and without cerebrovascular disease (CVD).; Methods: Re-contact follow-up study conducted in 2004 of 548 patients who had previously participated in RCTs with galantamine. Time to […]

Ye, Xingwang, Bhupathiraju, Shilpa N., Tucker, Katherine L.

Higher variety in fruit and vegetable intake has been associated with a lower risk of several chronic diseases. It remains unclear whether such associations exist relating to cognition. The authors examined associations between total quantity and variety in fruit and vegetable intake and cognitive function in a cross-sectional sample of 1412 Puerto Rican adults, aged […]

TAKAHASHI, Fumi, AWATA, Shuichi, Sakuma, Naoko, Inagaki, Hiroki, Ijuin, Mutsuo

Aim: The aim of this study was to evaluate the reliability and validity of A Quick Test of Cognitive Speed (AQT) for detecting early-stage dementia in the elderly Japanese population.; Methods: A total of 280 clinical participants (180 with mild Alzheimer’s disease, 43 with amnestic mild cognitive impairment, 32 with non-amnestic mild cognitive impairment and […]

Nurk, Eha, Refsum, Helga, Bjelland, Ingvar, Drevon, Christian A., Tell, Grethe S., Ueland, Per M., Vollset, Stein E., Engedal, Knut, Nygaard, Harald A., Smith, David A.

Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free choline and betaine. In a cross-sectional study, 2195 subjects (55 % women), aged 70-74 years, underwent extensive cognitive testing including the Kendrick Object Learning Test (KOLT), […]

Narme, Pauline, Clément, Sylvain, Ehrlé, Nathalie, Schiaratura, Loris, Vachez, Sylvie, Courtaigne, Bruno, Munsch, Frédéric, Samson, Séverine

Although musical interventions have recently gained popularity as a non-pharmacological treatment in dementia, there is still insufficient evidence of their effectiveness. To investigate this issue, a single-center randomized controlled trial was conducted with forty-eight patients with Alzheimer’s disease or mixed dementia to compare the effects of music versus cooking interventions in the emotional, cognitive, and […]