Fernández-Calvo, Bernardino, Rodríguez-Pérez, Roberto, Contador, Israel, Rubio-Santorum, Alicia, Ramos, Francisco

The study aims to assess the efficacy of the Big Brain Academy (BBA), a computerized cognitive training program (CT) based on video games, compared to the Integrated Psychostimulation Program (IPP), a classical CT tool for patients with Alzheimer’s disease (AD). A total of 45 patients with AD at the mild stage were randomly assigned to […]

Eckroth-Bucher, Margie, Siberski, James

Background: Cognitive decline leads to disability and increased health care expenditures.; Methods: Effectiveness of an intervention to stimulate multiple cognitive domains was determined using a format combining traditional and computer-based activities (Integrated Cognitive Stimulation and Training Program), 45 minutes a day, 2 days a week, for 6 weeks. Nonimpaired, mildly, and moderately-impaired participants > age […]

Wolinsky, Fredric D., Vander Weg, Mark W., Howren, M. Bryant, Jones, Michael P., Dotson, Megan M.

Background: Age-related cognitive decline is common and may lead to substantial difficulties and disabilities in everyday life. We hypothesized that 10 hours of visual speed of processing training would prevent age-related declines and potentially improve cognitive processing speed.; Methods: Within two age bands (50-64 and ≥ 65) 681 patients were randomized to (a) three computerized […]

Perilli, V., Lancioni, G. E., Hoogeveen, F., Caffo, A., Singh, N., O'Reilly, M., Sigafoos, J., Cassano, G., Oliva, D.

Background/aim: Two studies assessed the effectiveness of video prompting as a strategy to support persons with mild and moderate Alzheimer’s disease in performing daily activities.; Methods: In study I, video prompting was compared to an existing strategy relying on verbal instructions. In study II, video prompting was compared to another existing strategy relying on static […]

Liu, Yawu, Mattila, Jussi, Ruiz, Miguel Ángel Muñoz, Paajanen, Teemu, Koikkalainen, Juha, van Gils, Mark, Herukka, Sanna-Kaisa, Waldemar, Gunhild, Lötjönen, Jyrki, Soininen, Hilkka

Purpose: To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA) on MRI and CSF biomarkers.; Methods: Altogether 391 MCI cases (158 […]