This database contains 12 studies, archived under the term: "prevention"
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The PACE study: a randomized clinical trial of cognitive activity strategy training for older people with mild cognitive impairment
Vidovich, Mandy R.,
Lautenschlager, Nicola T.,
Flicker, Leon,
Clare, Linda,
McCaul, Kieran,
Almeida, Osvaldo P.
Objective: The role of cognition-focused interventions in reducing cognitive decline in older people remains uncertain. This study aimed to clarify whether a group cognitive activity (CA) strategy-training program would decrease the 2-year rate of cognitive decline of people with mild cognitive impairment (MCI).; Design: Randomized controlled trial.; Setting: One study site.; Participants: 160 older adults […]
Reducing dangerous nighttime events in persons with dementia by using a nighttime monitoring system
Rowe, Meredeth A.,
Kelly, Annette,
Horne, Claydell,
Lane, Steve,
Campbell, Judy,
Lehman, Brandy,
Phipps, Chad,
Keller, Meredith,
Pe Benito, Andrea
Background: Nighttime activity, a common occurrence in persons with dementia, increases the risk for injury and unattended home exits and impairs the sleep patterns of caregivers. Technology is needed that will alert caregivers of nighttime activity in persons with dementia to help prevent injuries and unattended exits. Methods: As part of a product development grant, […]
Anticholinergic drug use and risk for dementia: Target for dementia prevention
Jessen, Frank,
Kaduszkiewicz, Hanna,
Daerr, Moritz,
Bickel, Horst,
Pentzek, Michael,
Riedel-Heller, Steffi,
Wagner, Michael,
Weyerer, Siegfried,
Wiese, Birgitt,
van den Bussche, Hendrik,
Broich, Karl,
Maier, Wolfgang
An increasing number of longitudinal cohort studies have identified a risk increase for dementia by the chronic use of drugs with anticholinergic properties. The respective data from the German Study on Aging, Cognition and Dementia in Primary Care Patients (AgeCoDe) also showing risk increase (hazard ratio = 2.081) are reported here. The mechanisms by which […]
V-TIME: a treadmill training program augmented by virtual reality to decrease fall risk in older adults: study design of a randomized controlled trial
Mirelman, Anat,
Rochester, Lynn,
Reelick, Miriam,
Nieuwhof, Freek,
Pelosin, Elisa,
Abbruzzese, Giovanni,
Dockx, Kim,
Nieuwboer, Alice,
Hausdorff, Jeffrey M.
Background: Recent work has demonstrated that fall risk can be attributed to cognitive as well as motor deficits. Indeed, everyday walking in complex environments utilizes executive function, dual tasking, planning and scanning, all while walking forward. Pilot studies suggest that a multi-modal intervention that combines treadmill training to target motor function and a virtual reality […]
English longitudinal study of aging: Can Internet/E-mail use reduce cognitive decline?
Xavier, A. J.,
d'Orsi, E.,
de Oliveira, C. M.,
Orrell, M.,
Demakakos, P.,
Biddulph, J. P.,
Marmot, M. G.
Background: Cognitive decline is a major risk factor for disability, dementia, and death. The use of Internet/E-mail, also known as digital literacy, might decrease dementia incidence among the older population. The aim was to investigate whether digital literacy might be associated with decreased cognitive decline in older adulthood. Methods: Data from the English Longitudinal Study […]
A feasibility study and pilot randomised trial of a tailored prevention program to reduce falls in older people with mild dementia
Wesson, Jacqueline,
Clemson, Lindy,
Brodaty, Henry,
Lord, Stephen,
Taylor, Morag,
Gitlin, Laura,
Close, Jacqueline
Background: People with dementia have a disproportionately high rate of falls and fractures and poorer outcomes, yet there is currently no evidence to guide falls prevention in this population.; Methods: A randomised trial design was used to test feasibility of study components and acceptability of a home hazard reduction and balance and strength exercise fall […]
Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer’s disease: a pilot randomized controlled trial
Suttanon, P.,
Hill, K. D.,
Said, C. M.,
Williams, S. B.,
Byrne, K. N.,
LoGiudice, D.,
Lautenschlager, N. T.,
Dodd, K. J.
Objective: To evaluate the feasibility and safety of a home-based exercise programme for people with Alzheimer’s disease, and to provide preliminary evidence of programme effectiveness in improving balance and mobility and reducing falls risk.; Design: A randomized controlled trial.; Setting: Community.; Participants: Forty people with mild to moderate Alzheimer’s disease (mean age 81.9, SD 5.72; […]