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This database contains 14 studies, archived under the term: "on"

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The study protocol of a cluster-randomised controlled trial of family-mediated personalised activities for nursing home residents with dementia
Background: Following admission to a nursing home, the feelings of depression and burden that family carers may experience do not necessarily diminish. Additionally, they may experience feelings of guilt and grief for the loss of a previously close relationship. At the same time, individuals with dementia may develop symptoms of depression and agitation (BPSD) that […]

Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease
Purpose: Brief, effective models of patient genetic education are needed for common, complex diseases. Using Alzheimer disease as a model, we compared participants’ risk knowledge and recall in extended versus condensed education protocols.; Methods: A four-site randomized clinical trial enrolled 280 first-degree relatives of individuals with Alzheimer disease (mean age = 58 years, 71% female); […]

Viewing Art on a Tablet Computer: A Well-Being Intervention for People With Dementia and Their Caregivers
BACKGROUND: Art-based interventions have been shown to be beneficial for the well-being of people with dementia and their caregivers. This article explored whether such interventions can be delivered via a touchscreen tablet device displaying art images. METHOD: Twelve pairs of volunteers with dementia and informal caregivers were recruited (N = 24). A quasi-experimental mixed-methods within-subjects […]

‘What I want to do is get half a dozen of them and go and see Simon Cowell’: Reflecting on participation and outcomes for people with dementia taking part in a creative musical project
This paper presents the findings from an evaluation of a creative musical project led by Scottish Opera. The project included people with dementia and their carers in the development, writing, design and performance of a musical production about their experiences of love. The project involved professional singers, artists and choreographers from the opera company. Activities […]

Study protocol for the recreational stimulation for elders as a vehicle to resolve delirium superimposed on dementia (Reserve For DSD) trial
Background: Delirium is a state of confusion characterized by an acute and fluctuating decline in cognitive functioning. Delirium is common and deadly in older adults with dementia, and is often referred to as delirium superimposed on dementia, or DSD. Interventions that treat DSD are not well-developed because the mechanisms involved in its etiology are not […]

Pilot study of a nonpharmacological intervention for delirium superimposed on dementia
Delirium is a common neuropsychiatric syndrome that occurs most frequently in older adults with dementia and is referred to as delirium superimposed on dementia (DSD). Our aim in this pilot project was to demonstrate that implementation of cognitively stimulating activities is clinically feasible and has potential to reduce delirium severity and duration and functional loss […]

Randomised, multicentre, placebo-controlled, double-blind crossover study investigating the effect of solifenacin and oxybutynin in elderly people with mild cognitive impairment: the SENIOR study
Background: Compared with younger people, the elderly are more likely to suffer from overactive bladder (OAB) and to have other chronic conditions that affect physical or cognitive function. Despite this, there are few data on the cognitive safety of antimuscarinic agents in older patients and none that examine the effect of these agents on those […]

The long-term effect of group living homes versus regular nursing homes for people with dementia on psychological distress of informal caregivers
Objective: In this follow-up study, the long-term influence of group living homes (GLHs) on informal caregiver distress was compared with modern yet regular nursing homes (NHs).; Method: Informal caregivers of GLH (N = 37) and NH residents (N = 49) were studied at the time of admission, 6 months thereafter, and approximately 24 months after […]

Current treatments of Alzheimer disease: are main caregivers satisfied with the drug treatments received by their patients?
Background/aims: A full comparison of the satisfaction with treatment using the current Alzheimer’s disease (AD) therapies from the perspective of caregivers has not yet been done. The aim of this study was thus to find out the degree of satisfaction with the main available drug treatments in monotherapy for AD from this point of view.; […]

Agitation in nursing home residents with dementia (VIDEANT trial): effects of a cluster-randomized, controlled, guideline implementation trial
Objective: To test the effect of a complex guideline-based intervention on agitation and psychotropic prescriptions.; Design, Setting, Participants: Cluster randomized controlled trial (VIDEANT) with blinded assessment of outcome in 18 nursing homes in Berlin, Germany, comprising 304 dementia patients.; Intervention: Training, support, and activity therapy intervention, delivered at the level of each nursing home, focusing […]

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