Crichton, Georgina E., Murphy, Karen J., Howe, Peter R.C., Buckley, Jonathan D., Bryan, Janet

All individuals will experience some degree of cognitive impairment in their later years. Diet is one readily modifiable factor that may influence cognitive function and psychological well-being. Very little research has considered the potential role of dairy foods in modulating cognitive and psychological functions. The objective of this study was to determine the effect of […]

Zheng, Ling, Mack, Wendy J., Dagerman, Karen S., Hsiao, John K., Lebowitz, Barry D., Lyketsos, Constantine G., Stroup, T. Scott, Sultzer, David L., Tariot, Pierre N., Vigen, Cheryl, Schneider, Lon S.

Objective: The second-generation antipsychotics are associated with metabolic abnormalities in patients with schizophrenia. Elderly patients with Alzheimer’s disease are frequently treated with these antipsychotics, but limited data are available on their metabolic effects.; Method: The authors assessed 186 male and 235 female Alzheimer’s disease outpatients from the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer’s Disease (CATIE-AD) […]

Keller, Lina, Xu, Weili, Wang, Hui-Xin, Winblad, Bengt, Fratiglioni, Laura, Graff, Caroline

The FTO gene has been shown to have a small but robust effect on body mass index (BMI) and to increase the risk for diabetes. Both high BMI and diabetes are vascular risk factors that might play a role in the development of Alzheimer’s disease (AD) and dementia. Thus, our aim was to explore the […]

Virta, Jyri J., Heikkilä, Kauko, Perola, Markus, Koskenvuo, Markku, Räihä, Ismo, Rinne, Juha O., Kaprio, Jaakko

Cardiovascular risk factors increase the risk of dementia in later life. The aims of the current study were to assess the effect of multiple midlife cardiovascular risk factors on the risk of cognitive impairment in later life, and to assess the validity of the previously suggested CAIDE Study risk score predicting dementia risk 20 years later. […]

Benito-León, J., Mitchell, A. J., Hernández-Gallego, J., Bermejo-Pareja, F.

Background and Purpose: Studies of high body mass index (BMI) and cognition in the elderly have shown conflicting results. While some studies have shown a detrimental effect of high BMI on cognitive function, others have observed beneficial effects on cognition. Our aim was to assess cognitive function in a large population-based sample of overweight (BMI […]