Hill, Keith D., LoGiudice, Dina, Lautenschlager, Nicola T., Said, Catherine M., Dodd, Karen J., Suttanon, Plaiwan

Background: Balance dysfunction and falls are common problems in later stages of dementia. Exercise is a well-established intervention to reduce falls in cognitively intact older people, although there is limited randomised trial evidence of outcomes in people with dementia. The primary objective of this study is to evaluate whether a home-based balance exercise programme improves […]

Lucetti, Claudio, Logi, Chiara, Del Dotto, Paolo, Berti, Caterina, Ceravolo, Roberto, Baldacci, Filippo, Dolciotti, Cristina, Gambaccini, Gianna, Rossi, Giuseppe, Bonuccelli, Ubaldo

Purpose: To evaluate levodopa responsiveness in patients with probable dementia with Lewy bodies (DLB) compared to early Parkinson’s disease (PD) patients.; Methods: Twenty four cases with DLB and 21 with PD underwent a baseline assessment with UPDRS (sub-item II and III) and an acute levodopa challenge test. Positive response to acute levodopa test was defined […]

Suttanon, P., Hill, K. D., Said, C. M., Williams, S. B., Byrne, K. N., LoGiudice, D., Lautenschlager, N. T., Dodd, K. J.

Objective: To evaluate the feasibility and safety of a home-based exercise programme for people with Alzheimer’s disease, and to provide preliminary evidence of programme effectiveness in improving balance and mobility and reducing falls risk.; Design: A randomized controlled trial.; Setting: Community.; Participants: Forty people with mild to moderate Alzheimer’s disease (mean age 81.9, SD 5.72; […]

Roach, Kathryn E., Tappen, Ruth M., Kirk-Sanchez, Neva, Williams, Christine L., Loewenstein, David

Objective: To determine whether an activity specific exercise program could improve ability to perform basic mobility activities in long-term care residents with Alzheimer disease (AD).; Design: Randomized, controlled, single-blinded clinical trial.; Setting: Residents of 7 long-term care facilities.; Participants: Eighty-two long-term care residents with mild to severe AD.; Intervention: An activity specific exercise program was […]

Quinn, L., Debono, K., Dawes, H., Rosser, A. E., Nemeth, A. H., Rickards, H., Tabrizi, S. J., Quarrell, O., Trender-Gerhard, I., Kelson, M. J., Townson, J., Busse, M.

Background: Task-specific training may be a suitable intervention to address mobility limitations in people with Huntington disease (HD).; Objective: The aim of this study was to assess the feasibility and safety of goal-directed, task-specific mobility training for individuals with mid-stage HD.; Design: This study was a randomized, blinded, feasibility trial; participants were randomly assigned to […]

Kovács, E., Sztruhár Jónásné, I., Karóczi, C. K., Korpos, A., Gondos, T.

Background: Exercise programs have important role in prevention of falls, but to date, there are conflicting findings about the effects of exercise programs on balance, functional performance and fall risk among cognitively impaired older adults. AIM. To investigate the effects of a multimodal exercise program on static and dynamic balance, and risk of falls in […]

Kloos, A. D., Fritz, N. E., Kostyk, S. K., Young, G. S., Kegelmeyer, D. A.

Objective: To investigate the feasibility, acceptability, and safety of a supervised video game exercise program administered via Dance Dance Revolution in individuals with Huntington’s disease.; Design: A cross-over, controlled, single-blinded, six-week trial.; Setting: Home-based.; Participants: Eighteen ambulatory individuals with Huntington’s disease (seven male, mean age 50.7 SD 14.7).; Interventions: Participants played the Dance Dance Revolution […]