Utumi, Yushi, Iseki, Eizo, Murayama, Norio, Nozawa, Motohiro, Kumagai, Ryo, Matsubara, Youichiro, Ichimiya, Yosuke, Arai, Heii

Background: Functional gastrointestinal symptoms are frequently found in elderly dementia patients. In such a case, we attempt treatment by the administration of antidepressants or second-generation antipsychotics. However, these medications have a risk of side-effects. In the present study, we carried out oral administration of Rikkunshi-to to elderly dementia patients with appetite loss, and examined its […]

Ashford, J. W., Adamson, M., Beale, T., La, D., Hernandez, B., Noda, A., Rosen, A., O'Hara, R., Fairchild, J. K., Spielman, D., Yesavage, J. A.

Objectives: Magnetic Resonance Spectroscopy (MRS) may provide a precise and reliable assessment of the extent and severity of neural tissue loss caused by various diseases. In particular, the N-Acetyl Aspartate (NAA) and Creatine (Cr) ratio has been found to be an indicator of the degree of neuronal loss in Alzheimer’s disease (AD). Memantine is thought […]

Logsdon, Rebecca G., Pike, Kenneth C., McCurry, Susan M., Hunter, Patricia, Maher, Joanne, Snyder, Lisa, Teri, Linda

Objectives: This article describes results of a randomized controlled trial comparing a time-limited early-stage memory loss (ESML) support group program conducted by a local Alzheimer’s Association chapter to a wait-list (WL) control condition.; Methods: One hundred and forty-two dyads were randomized in blocks to ESML (n = 96) or WL (n = 46). Mean age […]

Richard, E., Gouw, A. A., Scheltens, P., van Gool, W. A.

Background and Purpose: White matter lesions (WMLs) and cerebral infarcts are common findings in Alzheimer disease and may contribute to dementia severity. WMLs and lacunar infarcts may provide a potential target for intervention strategies. This study assessed whether multicomponent vascular care in patients with Alzheimer disease with cerebrovascular lesions slows progression of WMLs and prevents […]