Rothi, Leslie J. Gonzalez, Fuller, Renee, Leon, Susan A., Kendall, Diane, Moore, Anna, Wu, Samuel S., Crosson, Bruce, Heilman, Kenneth M., Nadeau, Stephen E.

Six individuals with probable Alzheimer’s disease (AD) participated in a phase 1 study employing a repeated measures, parallel baseline design testing the hypothesis that error-free experience during word production practice combined with an acetyl cholinesterase inhibitor would improve confrontation naming ability. While acetyl cholinesterase inhibitors are safe and delay cognition decline associated with AD, improvement […]

Noonan, Krist A., Pryer, Louise R., Jones, Roy W., Burns, Alistair S., Lambon Ralph, Matthew A.

Developing rehabilitation techniques to combat cognitive decline is a key goal of healthcare strategies aimed at promoting increased longevity and better quality of life for individuals with Alzheimer’s disease (AD). In AD, problems with episodic memory and word-finding greatly affect everyday life and, as such, these symptoms provide a clear clinical target for therapeutic interventions. […]

Man, David, Lee, Grace, Yu, Edwin, Yip,

Background: Improving the situation in older adults with cognitive decline and evidence of cognitive rehabilitation is considered crucial in long-term care of the elderly. The objective of this study was to implement a computerized errorless learning-based memory training program (CELP) for persons with early Alzheimer’s disease, and to compare the training outcomes of a CELP […]

Lea, Emma, Marlow, Annette, Bramble, Marguerite, Andrews, Sharon, Crisp, Elaine, Eccleston, Claire, Mason, Ron, Robinson, Andrew

The residential aged care sector is reportedly a less attractive career choice for nursing students than other sectors. Research shows that students are often fearful of working with residents with dementia when they are inadequately supported on clinical placements by aged care staff. Thirty first-year nursing students attended a 2-week placement in one of two […]

Haslam, Catherine, Moss, Zoë, Hodder, Kathryn

A growing trend in memory rehabilitation is to combine learning principles to enhance treatment effects. While this makes intuitive sense, little is known about the added value of incorporating each method. A further complication is that some interventions, although primarily based on one learning principle, actually incorporate several, which again adds to the difficulty in […]

Granata, C., Pino, M., Legouverneur, G., Vidal, J. S., Bidaud, P., Rigaud, A. S.

Background: Socially assistive robotics for elderly care is a growing field. However, although robotics has the potential to support elderly in daily tasks by offering specific services, the development of usable interfaces is still a challenge. Since several factors such as age or disease-related changes in perceptual or cognitive abilities and familiarity with computer technologies […]

Duff, Melissa C., Gallegos, Diana R., Cohen, Neal J., Tranel, Daniel

Seminal work in Gary Van Hoesen’s laboratory at Iowa in the early 1980s established that the hallmark neuropathology of Alzheimer’s disease (AD; neurofibrillary tangles) had its first foothold in specific parts of the hippocampal formation and entorhinal cortex, effectively isolating the hippocampus from much of its input and output and causing the distinctive impairment of […]

Chapman, Robert M., Mapstone, Mark, Gardner, Margaret N., Sandoval, Tiffany C., McCrary, John W., Guillily, Maria D., Reilly, Lindsey A., DeGrush, Elizabeth

We analyzed verbal episodic memory learning and recall using the Logical Memory (LM) subtest of the Wechsler Memory Scale-III to determine how gender differences in AD compare to those seen in normal elderly and whether or not these differences impact assessment of AD. We administered the LM to both an AD and a Control group, […]