Thiyagesh, Subha N., Farrow, Tom F. D., Parks, Randolph W., Accosta-Mesa, Hector, Hunter, Michael D., Young, Claire, Wilkinson, lain D., Woodruff, Peter W. R.

Background/Aims: Visuospatial impairments are known to occur in Alzheimer’s disease (AD). We hypothesised that functional magnetic resonance imaging (fMRI) response in task-related brain regions would be impaired in patients with AD during the task and that treatment with acetyl cholinesterase inhibitors would enhance activations in brain regions concerned with this visual perceptual processing. Method: Ten […]

Weijenberg, Roxane Anthea Francesca, Lobbezoo, Frank, Knol, Dirk Lucas, Tomassen, Jori, Scherder, Erik Johan Anton

Background: Worldwide, millions of people are suffering from dementia and this number is rising. An index of quality of life (QoL) can describe the impact a disease or treatment has on a person’s wellbeing. QoL comprises many variables, including physical health and function, and mental health and function. QoL is related to masticatory ability and […]

Thompson, Hilaire J., Rivara, Frederick P., Nathens, Avery, Wang, Jin, Jurkovich, Gregory J., Mackenzie, Ellen J.

Objective: The aim of this study was to develop and validate a comorbidity index to predict the risk of mortality associated with chronic health conditions following a traumatic injury.; Summary Background Data: Currently available comorbidity adjustment tools do not account for certain chronic conditions, which may influence outcome following traumatic injury or they have not […]

Johnson, D. K., Niedens, M., Wilson, J. R., Swartzendruber, L., Yeager, A., Jones, K.

Purpose: Although declines in memory and attention are hallmark symptoms of Alzheimer’s disease (AD), noncognitive symptoms are prevalent. Over 80% of individuals will experience neuropsychiatric symptoms, which complicates symptom profiles. Research indicates a community-integrated response to dementia crisis can reduce negative consequences attributed to crisis including increased caregiver burden, increased health care costs, and premature […]