Wagg, Adrian, Dale, Mark, Tretter, Reiner, Stow, Bridget, Compion, Gerhard

Background: Compared with younger people, the elderly are more likely to suffer from overactive bladder (OAB) and to have other chronic conditions that affect physical or cognitive function. Despite this, there are few data on the cognitive safety of antimuscarinic agents in older patients and none that examine the effect of these agents on those […]

Smit, Dieneke, te Boekhorst, Selma, de Lange, Jacomine, Depla, Marja F.I.A., Eefsting, Jan A., Pot, Anne-Margriet

Objective: In this follow-up study, the long-term influence of group living homes (GLHs) on informal caregiver distress was compared with modern yet regular nursing homes (NHs).; Method: Informal caregivers of GLH (N = 37) and NH residents (N = 49) were studied at the time of admission, 6 months thereafter, and approximately 24 months after […]

Kazui, Hiroaki, Mori, Etsuro, Hashimoto, Masaaki, Ishikawa, Masatsune, Hirono, Nobutsugu, Takeda, Masatoshi

Background/aims: Patients with idiopathic normal pressure hydrocephalus (iNPH) are often given shunt operations to reduce the triad symptoms (cognitive impairment, gait disturbance and urinary disturbance). We examined whether they also reduce caregiver burden.; Methods: The personal strain (PS) and role strain (RS) factors, which are related to the stress and constraints, respectively, on the caregivers […]

Flynn Longmire, Crystal V., Drye, Lea T., Frangakis, Constantine E., Martin, Barbara K., Meinert, Curtis L., Mintzer, Jacobo E., Munro, Cynthia A., Porsteinsson, Anton P., Rabins, Peter V., Rosenberg, Paul B., Schneider, Lon S., Weintraub, Daniel, Lyketsos, Constantine G.

Objective: We wanted to assess if sertraline treatment (versus placebo) or remission of depression at 12 weeks (versus nonremission) in Alzheimer patients is associated with improved caregiver well being.; Methods: We conducted a randomized, double-blind, placebo-controlled clinical trial of the efficacy and safety of sertraline for the treatment of depression in individuals with Alzheimer disease […]

Anderson, Katrina, Bird, Michael, MacPherson, Sarah, McDonough, Vikki, Davis, Terri

There is increasing literature on multisensory therapy or Snoezelen, with some evidence suggesting it promotes positive mood and reduces maladaptive behavior in people with dementia. We undertook a pilot evaluation of a Snoezelen room in residential care and compared effects with a condition in which staff took residents out to a garden. This study was […]