Callahan, Christopher M., Boustani, Malaz A., Schmid, Arlene A., Austrom, Mary G., Miller, Douglas K., Gao, Sujuan, Morris, Carrie S., Vogel, Mickey, Hendrie, Hugh C.

Background: Given the current lack of disease-modifying therapies, it is important to explore new models of longitudinal care for older adults with dementia that focus on improving quality of life and delaying functional decline. In a previous clinical trial, we demonstrated that collaborative care for Alzheimer’s disease reduces patients’ neuropsychiatric symptoms as well as caregiver […]

Martín-Carrasco, Manuel, Martín, Manuel Franco, Valero, Carmelo Pelegrín, Millán, Pedro Roy, García, Celso Iglesias, Montalbán, Salvador Ros, Vázquez, Ana Luisa Gobartt, Piris, Sonia Pons, Vilanova, Montserrat Balañá

Objectives: Caregivers of patients with Alzheimer’s disease (AD) experience physical and psychological stress due to the caring experience. This study evaluated the benefits of a Psychoeducational Intervention Program (PIP) on caregiver burden in southern Europe.; Methods: A multicentre, prospective, randomised study was conducted. One hundred and fifteen caregivers of patients with clinical diagnosis of AD […]

Chiatti, Carlos, Masera, Filippo, Rimland, Joseph M., Cherubini, Antonio, Scarpino, Osvaldo, Spazzafumo, Liana, Lattanzio, Fabrizia

Background: The epidemic of Alzheimer’s disease (AD) represents a significant challenge for the health care and social service systems of many developed countries. AD affects both patients and family caregivers, on whom the main burden of care falls, putting them at higher risk of stress, anxiety, mortality and lower quality of life. Evidence remains controversial […]

Pitkälä, Kaisu H., Pöysti, Minna M., Laakkonen, Marja-Liisa, Tilvis, Reijo S., Savikko, Niina, Kautiainen, Hannu, Strandberg, Timo E.

Importance: Few rigorous clinical trials have investigated the effectiveness of exercise on the physical functioning of patients with Alzheimer disease (AD).; Objectives: To investigate the effects of intense and long-term exercise on the physical functioning and mobility of home-dwelling patients with AD and to explore its effects on the use and costs of health and […]

Paukert, Amber L., Calleo, Jessica, Kraus-Schuman, Cynthia, Snow, Lynn, Wilson, Nancy, Petersen, Nancy J., Kunik, Mark E., Stanley, Melinda A.

Background: Anxiety has a high prevalence among individuals with dementia, and it has a significant negative impact on their functioning; yet intervention studies are lacking. We developed Peaceful Mind, a cognitive-behavioral intervention for persons with dementia. In this paper, we describe the intervention and results of an open trial evaluating the feasibility and utility of […]

Karatay, G., Akkus, Y.

The purpose of this study was to test the effects of a multistimulant home-based intervention program on cognitive function, anxiety, and depression among older adults with cognitive impairment. This research is quasi-experimental and was designed in an effort to increase the cognitive capacity of individuals above the age of 60 with reduced cognitive capacities. Each […]