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This database contains 40 studies, archived under the term: "cost of illness"

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A community-based exercise programme to improve functional ability in people with Alzheimer’s disease: a randomized controlled trial

Rationale: Dementia is a common neurodegenerative condition in older age associated with functional decline across multiple domains. This decline impacts not only on the person with dementia, but also on their informal carers and health and aged care systems. With the number of people with dementia rapidly increasing and few effective treatments, there is now […]

Effectiveness of dementia follow-up care by memory clinics or general practitioners: randomised controlled trial

Objective: To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners.; Design: Multicentre randomised controlled trial.; Setting: Nine memory clinics and 159 general practitioners in the Netherlands.; Participants: 175 patients with a new diagnosis of mild to moderate dementia living in the community and their informal […]

Memory and communication support strategies in dementia: effect of a training program for informal caregivers

Background: People with dementia have a range of needs that are met by informal caregivers. A DVD-based training program was developed using research-based strategies for memory and communication in dementia. The effectiveness of the training on the caregiver experience and the well-being of the person with dementia was evaluated.; Methods: A pre-test/post-test controlled trial was […]

Effectivity of early psychosocial counselling for family caregivers in general practioner based dementia care

Background: Psychoeducation and professional support of family caregivers are regarded as important aspects in dementia care. In the context of a general practitioner’s (GP) based dementia care project we investigated if professional counselling after making a diagnosis of dementia can reduce the development of depression in family caregivers.; Methods: 42 patients with dementia and their […]

A benefit-finding intervention for family caregivers of persons with Alzheimer disease: study protocol of a randomized controlled trial

Background: Caregivers of relatives with Alzheimer’s disease are highly stressed and at risk for physical and psychiatric conditions. Interventions are usually focused on providing caregivers with knowledge of dementia, skills, and/or support, to help them cope with the stress. This model, though true to a certain extent, ignores how caregiver stress is construed in the […]

Effect of second-generation antipsychotics on caregiver burden in Alzheimer’s disease

Background: Alzheimer’s disease (AD) imposes a severe burden upon patients and their caregivers. Severity of psychiatric symptoms and behavioral disturbances is an important determinant of caregivers’ experience of burden. These symptoms may be improved with atypical antipsychotic treatment.; Objective: Data from the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer’s Disease (CATIE-AD) trial were used to evaluate […]

A randomized, double-blind, placebo-controlled trial of modafinil for the treatment of apathy in individuals with mild-to-moderate Alzheimer’s disease

Objective: This study examined the effects of modafinil on apathetic symptomatology, performance of activities of daily living (ADLs), and caregiver burden in individuals with Alzheimer’s disease (AD).; Method: 23 participants with a diagnosis of mild-to-moderate probable AD according to National Institute of Neurologic and Communicative Disorder and Stroke-Alzheimer’s Disease and Related Disorders criteria were randomized […]

Public-private partnerships improve health outcomes in individuals with early stage Alzheimer’s disease

Purpose: In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA), Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs) and their family caregivers (FCGs), therefore addressing an important public health concern.; Participants and Methods: A […]

Systematic care for caregivers of patients with dementia: a multicenter, cluster-randomized, controlled trial

Objective: To evaluate the effectiveness of the Systematic Care Program for Dementia (SCPD) on patient institutionalization and to determine the predictors of institutionalization.; Design: Single-blind, multicenter, cluster-randomized, controlled trial.; Setting: Six community mental health services (CMHSs) across the Netherlands.; Participants: A total of 295 patient-caregiver dyads referred to a CMHS with suspected patient dementia.; Intervention: […]

Randomized controlled trial of a dementia care programme for families of home-resided older people with dementia

Aim: This paper reports a study to examine the effectiveness of a 6-month dementia care programme for Chinese families living with and caring for a relative with dementia, compared with routine family support services in Hong Kong.; Background: Recognizing the adverse psychosocial health effects inherent in dementia care, different psychosocial interventions provided preliminary evidence of […]

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