Shen, Wei, Xiao, Yuanyuan, Ying, Xuhua, Li, Songtao, Zhai, Yujia, Shang, Xiaopeng, Li, Fudong, Wang, Xinyi, He, Fan, Lin, Junfen

Background: Laboratorial and epidemiological researches suggested that tea exhibited potential neuroprotective effect which may prevent cognitive impairment, but there were few data among the elderly aged 60 years and above in China.; Objective: The objective was to explore the relationship between characteristics of tea consumption and cognitive impairment.; Design: We analyzed the baseline data from […]

Zhang, Y., Lin, C., Zhang, L., Cui, Y., Gu, Y., Guo, J., Wu, D., Li, Q., Song, W.

OBJECTIVES: To explore the efficacy of Chinese herbal formula compared with donepezil 5 mg/day in patients with mild Alzheimer’s disease (AD). METHODS: Patients with mild AD meeting the criteria were randomized into Chinese herbal formula Yishen Huazhuo decoction (YHD) group and donepezil hydrochloride (DH) group during the 24-week trial. The outcomes were measured by ADAS-cog, […]

Cheng, Sheung-Tak, Lam, Linda C. W., Chan, Liliane C. K., Law, Alexander C. B., Fung, Ada W. T., Chan, Wai-chi, Tam, Cindy W. C., Chan, Wai-man

Background: This study investigated whether brief exposure to information has any effect on stigmatizing attitudes towards older people with dementia, and how people responded to this medical diagnosis.; Methods: 494 adults were randomly assigned to three groups differentiated by experimental conditions. Group A (control) responded to questions on stigma directly. Group B (symptom) read two […]

Wang, Tao, Huang, Qiu, Reiman, Eric M., Chen, Kewei, Li, Xia, Li, Guanjun, Lin, Zhiguang, Li, Chunbo, Xiao, Shifu

Most experts consider that memantine has a symptomatic treatment, but clinical trials have not yet provided compelling evidence to support a disease-modifying effect. We investigate the effects of memantine on clinical ratings; fluorodeoxyglucose positron emission tomography (FDG-PET) measurements, which can monitor disease-modifying effect; and cerebrospinal fluid (CSF) assays in patients with moderate to severe probable […]

Jiang, Changchuan, Xu, Yong

Objectives: The ability to perform instrumental activities of daily living (IADL) is thought to be relatively intact for people with mild cognitive impairment (MCI). Doing housework as part of IADL is an important skill needed for older people to live independently and successfully. A limited number of studies explore the association between MCI and doing […]

Kwok, T C Y, Lam, L C W, Sea, M M M, Goggins, W, Woo, J

Background/objectives: To examine whether dietary interventions promote intakes of fruit, vegetable, fish and lower salt intake were effective in preventing cognitive decline in older people. Dietary factors have been associated with cognitive function in older people.; Subjects/methods: A total of 429 non-demented subjects in 14 old age hostels, with an average age of 83 years, […]

Kwok, Timothy CY, Bai, Xue, Li, Jessie CY, Ho, Florence KY, Lee, Tatia MC

Objective: This study examines the short-term and long-term effects of a cognitive training (CT) program in enhancing cognitive function of older people with subjective memory complaints.; Methods: A single-blind randomized placebo-controlled trial was carried out in a sample of 223 older adults aged 65 years or above with subjective memory complaints in Hong Kong. They […]