Heaton, Robert K., Franklin, Donald R., Ellis, Ronald J., McCutchan, J. Allen, Letendre, Scott L., Leblanc, Shannon, Corkran, Stephanie H., Duarte, Nichole A., Clifford, David B., Woods, Steven P., Collier, Ann C., Marra, Christina M., Morgello, Susan, Mindt, Monica Rivera, Taylor, Michael J., Marcotte, Thomas D., Atkinson, J. Hampton, Wolfson, Tanya, Gelman, Benjamin B., McArthur, Justin C., Simpson, David M., Abramson, Ian, Gamst, Anthony, Fennema-Notestine, Christine, Jernigan, Terry L., Wong, Joseph, Grant, Igor

Combination antiretroviral therapy (CART) has greatly reduced medical morbidity and mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders (HAND) continue to be reported. Because large HIV-infected (HIV+) and uninfected (HIV-) groups have not been studied with similar methods in the pre-CART and CART eras, it is unclear whether CART has changed the […]

Gandhi, Nishiena S., Skolasky, Richard L., Peters, Katherine B., Moxley, Richard T. th, Creighton, Jason, Roosa, Heidi Vornbrock, Selnes, Ola A., McArthur, Justin, Sacktor, Ned

The objectives of this study are to compare the results of newer performance-based functional assessments in the study of HIV-associated neurocognitive disorders (HAND) and to correlate these functional assessments with specific levels of severity of HAND. One hundred fourteen HIV+ subjects in an existing cohort were evaluated with a medical history, neurological exam, neuropsychological test […]

Simioni, Samanta, Cavassini, Matthias, Annoni, Jean-Marie, Rimbault Abraham, Aline, Bourquin, Isabelle, Schiffer, Véronique, Calmy, Alexandra, Chave, Jean-Philippe, Giacobini, Ezio, Hirschel, Bernard, Du Pasquier, Renaud A.

Objective: To determine the prevalence of cognitive complaints and HIV-associated neurocognitive disorders (HANDs) in a cohort of aviremic HIV-positive patients. To evaluate the relevance of the HIV dementia scale to detect HANDs.; Design: Assessment of HANDs with neuropsychological tests.; Methods: Two hundred HIV-infected patients with undetectable HIV-1 RNA concentrations in the plasma, no history of […]