Rondanelli, Mariangela, Opizzi, Annalisa, Faliva, Milena, Mozzoni, Marco, Antoniello, Neldo, Cazzola, Roberta, Savarè, Rita, Cerutti, Renata, Grossi, Enzo, Cestaro, Benvenuto

Age-related changes in nutritional status can play an important role in brain functioning. Specific nutrient deficiencies in the elderly may exacerbate pathological processes in the brain. Consequently, the potential of nutritional intervention to prevent or delay cognitive impairment and the development of dementia is an important topic. A randomized, double-blind, placebo-controlled trial has been performed […]

Pond, Constance D., Brodaty, Henry, Stocks, Nigel P., Gunn, Jane, Marley, John, Disler, Peter, Magin, Parker, Paterson, Nerida, Horton, Graeme, Goode, Susan, Paine, Bronwen, Mate, Karen E.

Background: Dementia is increasing in prevalence as the population ages. An earlier rather than later diagnosis allows persons with dementia and their families to plan ahead and access appropriate management. However, most diagnoses are made by general practitioners (GPs) later in the course of the disease and are associated with management that is poorly adherent […]

Iliffe, Steve, Koch, Tamar, Jain, Priya, Lefford, Frances, Wong, Geoffrey, Warner, Alex, Wilcock, Jane

Background: Dementia syndromes are under-diagnosed and under-treated in primary care. Earlier recognition of and response to dementia syndrome is likely to enhance the quality of life of people with dementia, but general practitioners consistently report limited skills and confidence in diagnosis and management of this condition. Changing clinical practice is difficult, and the challenge for […]

van den Bogaard, S. J. A., Dumas, E. M., Hart, E. P., Milles, J., Reilmann, R., Stout, J. C., Craufurd, D., Gibbard, C. R., Tabrizi, S. J., van Buchem, M. A., van der Grond, J., Roos, R. A. C.

Background and Purpose: MTI is a quantitative MR imaging technique that has recently demonstrated structural integrity differences between controls and patients with HD. Potentially, MTI can be used as a biomarker for monitoring disease progression. To establish the value of MTI as a biomarker, we aimed to examine the change in these measures during the […]

Schmid, R., Eschen, A., Rüegger-Frey, B., Martin, M.

Background: There is growing evidence that individuals with cognitive impairment and dementia require systematic assessment of needs for the selection of optimal treatments. Currently no valid instrument is applicable for illness-related need assessment in this growing population.; Method: The purpose of this study was to develop and validate a new instrument (“Bedürfnisinventar bei Gedächtnisstörungen”, BIG-65) […]

Raetz, Paige B., LeBlanc, Linda A., Baker, Jonathan C., Hilton, Laura C.

Paired-stimulus preference assessments have been used effectively with individuals with dementia to identify stimuli to increase engagement and to minimize negative affect and problem behavior.We evaluated whether a multiple-stimulus without replacement preference assessment could be used with older adults with dementia and whether preferences remained stable over time. Seven participants completed preference assessments and confirmatory […]

Gitlin, Laura N, Mann, William C, Vogel, W, Arthur, Paul B

Background: Behavioral symptoms accompanying dementia are associated with increased health care costs, reduced quality of life and daily functioning, heightened family caregiver burden, and nursing home placement. Standard care typically involves pharmacologic agents, but these are, at best, modestly effective, carry serious risks, including mortality, and do not address behavioral symptoms families consider most distressful […]

Gies, Cheryl, Pierce, Linda, Steiner, Victoria, van der Bijl, Joan, Salvador, Diane

Purpose and Design: Most of the 5.4 million Americans with dementia are cared for by family members who experience care needs and time constraints. This quasi-experimental study examined the experience of using a psychosocial assessment instrument to understand caregiver needs delivered in an interview versus a self-administered web-based format.; Methods: Ten family caregivers were randomized […]