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Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition

Objective: To compare the relative effects of conjugated equine estrogens (CEE), raloxifene, and tamoxifen therapies on cognition among women aged > or =65 years.; Methods: Annual Modified Mini-Mental State (3MS) examinations were used to assess global cognitive function in the two randomized placebo-controlled clinical trials of CEE therapies of the Women’s Health Initiative Memory Study […]

Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial

Context: The herbal product Ginkgo biloba is taken frequently with the intention of improving cognitive health in aging. However, evidence from adequately powered clinical trials is lacking regarding its effect on long-term cognitive functioning.; Objective: To determine whether G. biloba slows the rates of global or domain-specific cognitive decline in older adults.; Design, Setting, and […]

Validation of a cognitive assessment battery administered over the telephone

Objectives: To evaluate the validity and reliability of a cognitive test battery and questionnaires administered by telephone.; Design: Observational study; 110 participants randomly assigned to receive two administrations of the same cognitive test battery 6 months apart in one of four combinations (Time 1 administration/Time 2 administration): telephone/telephone, telephone/face to face, face to face/telephone, face […]