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Effectiveness of a specific care plan in patients with Alzheimer’s disease: cluster randomised trial (PLASA study)

Objective: To test the effectiveness of a comprehensive specific care plan in decreasing the rate of functional decline in patients with mild to moderate Alzheimer’s disease compared with usual care in memory clinics.; Design: Cluster randomised trial.; Setting: 50 memory clinics in France.; Participants: Patients with Alzheimer’s disease (mini-mental state examination score 12-26). 1131 patients […]

A follow‐up intervention in severely demented patients after discharge from a special Alzheimer acute care unit: Impact on early emergency room re‐hospitalization rate

Background: Emergency room (ER) re-hospitalizations are prevalent in severe Alzheimer’s disease affected older patients. Design: Quasi-experimental before and after study. Setting: Discharge of severely demented patients from a Special Alzheimer Acute Care Unit. Participants: A total of 390 patients hospitalized in the unit from 2007 through 2009, with at least one of the following characteristics: […]

Impact of a therapeutic educational program on quality of life in Alzheimer’s disease: Results of a pilot study

Background: Therapeutic patient education is expanding in the field of Alzheimer’s disease (AD). Objective: To evaluate the impact of a therapeutic educational program, on AD-affected patients and their caregivers, living in the community, on the patient’s quality of life. Methods: Non experimental before and after study. Patient/caregiver dyads were recruited in the geriatric department of […]

Angiotensin-converting enzyme inhibitors and Alzheimer’s disease progression in older adults: results from the Réseau sur la Maladie d’Alzheimer Français cohort

Objectives: To assess whether angiotensin-converting enzyme inhibitor (ACE-I) treatment is associated with less cognitive decline in older adults with Alzheimer’s disease (AD) than in those using other hypertensive or no drugs.; Design: Four-year prospective multicenter cohort study with a biannual assessment.; Setting: Memory clinics from 16 university hospitals in France.; Participants: Community-dwelling older adults with […]