MODEM Dementia Evidence Database

Is sertraline treatment or depression remission in depressed Alzheimer patients associated with improved caregiver well being? Depression in Alzheimer’s Disease Study 2

Flynn Longmire, Crystal V., Drye, Lea T., Frangakis, Constantine E., Martin, Barbara K., Meinert, Curtis L., Mintzer, Jacobo E., Munro, Cynthia A., Porsteinsson, Anton P., Rabins, Peter V., Rosenberg, Paul B., Schneider, Lon S., Weintraub, Daniel, Lyketsos, Constantine G.

...Objective: We wanted to assess if sertraline treatment (versus placebo) or remission of depression at 12 weeks (versus nonremission) in Alzheimer patients is associated with improved caregiver well being.;...

Depression as a risk factor or prodromal feature for dementia? Findings in a population-based sample of Swedish twins

Brommelhoff, Jessica A., Gatz, Margaret, Johansson, Boo, McArdle, John J., Fratiglioni, Laura, Pedersen, Nancy L.

...This study tested whether history of depression is associated with an increased likelihood of dementia, and whether a first depressive episode earlier in life is associated with increased dementia...

A structural multidisciplinary approach to depression management in nursing-home residents: a multicentre, stepped-wedge cluster-randomised trial

Leontjevas, Ruslan, Gerritsen, Debby L, Smalbrugge, Martin, Teerenstra, Steven, Vernooij-Dassen, Myrra JFJ, Koopmans, Raymond TCM

...Background: Depression in nursing-home residents is often under-recognised. We aimed to establish the effectiveness of a structural approach to its management.; Methods: Between May 15, 2009, and April 30,...

Problem adaptation therapy for older adults with major depression and cognitive impairment: A randomized clinical trial

Kiosses, Dimitris N., Ravdin, Lisa D., Gross, James J., Raue, Patrick, Kotbi, Nabil, Alexopoulos, George S.

...IMPORTANCE: Problem adaptation therapy (PATH) is a treatment for older adults with major depression, cognitive impairment (from mild cognitive deficits to moderate dementia), and disability. Antidepressants have limited efficacy...

More insight into the concept of apathy: a multidisciplinary depression management program has different effects on depressive symptoms and apathy in nursing homes

Leontjevas, Ruslan, Teerenstra, Steven, Smalbrugge, Martin, Vernooij-Dassen, Myrra J. F. J., Bohlmeijer, Ernst T., Gerritsen, Debby L, Koopmans, Raymond T. C. M.

...Background: Apathy is common in nursing home (NH) residents and it overlaps with depression. This study examines the effects of a multidisciplinary depression program on apathy and depressive motivational...

Association of depression with accelerated cognitive decline among patients with type 2 diabetes in the ACCORD-MIND trial

Sullivan, Mark D., Katon, Wayne J., Lovato, Laura C., Miller, Michael E., Murray, Anne M., Horowitz, Karen R., Bryan, R. Nick, Gerstein, Hertzel C., Marcovina, Santica, Akpunonu, Basil E., Johnson, Janice, Yale, Jean Francois, Williamson, Jeff, Launer, Lenore J.

...Importance: Depression has been identified as a risk factor for dementia among patients with type 2 diabetes mellitus but the cognitive domains and patient groups most affected have not...

Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial

...Background: Depression is common in dementia but the evidence base for appropriate drug treatment is sparse and equivocal. We aimed to assess efficacy and safety of two of the...

Animal-assisted therapy and agitation and depression in nursing home residents with dementia: A matched case–control trial

Majić, Tomislav, Gutzmann, Hans, Heinz, Andreas, Lang, Undine E., Rapp, Michael A.

...Objectives: To investigate the efficacy of animal-assisted therapy (AAT) on symptoms of agitation/aggression and depression in nursing home residents with dementia in a randomized controlled trial. Previous studies have...

The impact of group music therapy on depression and cognition in elderly persons with dementia: a randomized controlled study

Chu, H., Yang, C.-Y., Lin, Y., Ou, K.-L., Lee, T.-Y., O'Brien, A. P., Chou, K.-R.

...Objective: The aims of this study were to determine the effectiveness of group music therapy for improving depression and delaying the deterioration of cognitive functions in elderly persons with...

Validity of the geriatric depression scale in nursing home residents: comparison of GDS-15, GDS-8, and GDS-4

Allgaier, Antje-Kathrin, Kramer, Dietmar, Mergl, Roland, Fejtkova, Sabina, Hegerl, Ulrich

...Objective: To assess and compare the validity of the German 15-item version and shortened versions of the Geriatric Depression Scale (GDS) for early detection of depression in nursing home...

Your search has found 150 articles in the database for the term 'Depression'